adrenocortical carcinoma

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adrenocortical carcinoma

Oncology A rare–≤ 2 in 106/yr tumor of the adrenal cortex; average age 46; ♂:♀ ratio 1:2.5 Clinical ± 70% of Pts with AC have endocrine symptoms due to excess secretion of glucocorticoids and/or androgens, less commonly due to excess mineralocorticoids or estrogens Management Surgical resection, mitotane. See Mitotane.
Adrenocortical cancer
Stage I
CA < 5 cms; no spread to periadrenal tissues
Stage II
CA > 5 cms; no spread to periadrenal tissues
Stage III
CA spread to periadrenal tissues or lymph nodes
Stage IV
CA spread to regional tissues or organs, to lymph nodes around adrenal cortex, or metastasized
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References in periodicals archive ?
Two weeks later, on Monday, April 1, she was diagnosed with stage three adrenal carcinoma, a rare disease caused by cancerous cells in the adrenal - or hormone - glands.
Adrenal carcinoma with intravenous extension into the tricuspid valvular plane in a patient with patent foramen ovale.
The differential diagnoses include neuroblastoma, ganglioneuroblastoma, adrenal hemorrhage, granulomatous disease/infection, lymphoma, and adrenal carcinoma.
A case of androgen-secreting adrenal carcinoma with non-classical congenital adrenal hyperplasia.
20 (31.7%) had Cushing's syndrome, 4 (6.3%) had primary aldosteronism, 5 (7.9%) had adrenal carcinoma, and 4 (6.3%) had pheochromocytomas.
Robertson, "Hyperaldosteronism from Adrenal Carcinoma," British Medical Journal, vol.
Histopathological examination of the adrenalectomy specimens revealed bilateral adrenal carcinoma with sarcomatous component.
In conclusion, ovarian teratoma and metastatic adrenal carcinoma are two unusual causes of IO in cattle.
The patient had pre-operative fine needle biopsy suggestive of RCC without any clinical sign of adrenal carcinoma. However, per operative the mass seemed to be of adrenal origin and was distinct from kidney which was preserved.
The use of an immunohistochemical panel, including EMA, cytokeratins, CD10, inhibin, S100 protein, NSE, and chromogranin has been proposed for the differential diagnosis of renal HBL versus CCRCC, adrenal carcinoma, and paraganglioma.
Primary adrenal carcinoma (ACC) is a rare, aggressive malignancy arising from the adrenal cortex.