Adipostat | definition of Adipostat by Medical dictionary
Adipostat A hypothetical mechanism and set-point region that may reside in the ventromedial, lateral, and paraventricular nuclei of the hypothalamus and possibly elsewhere, which regulates body fat within a narrow range based on intake and energy expenditure. It appears (assuming this simplistic entity actually exists) to maintain the metabolic status quo, and modify behaviours traditionally perceived as voluntary—e.g., eating and physical activity—as well as metabolic activity to compensate for changes in diet.
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References in periodicals archive
The idea of a relatively simple hypothalamic adipostat
that had emerged about 20 years ago following the discovery of leptin has been replaced with an extensive neural network that encompasses most areas of the brain, including the cortico-limbic systems that make up >80% of the human brain.
Body weight 'set point' idea is supported by physiological mechanisms centered around sensing systems in adipose tissue that reflects fat stores and a receptor or "adipostat
" that is in the hypothalamic centres.
(28) This is an analogy to the thermostat--hence the name of "adipostat
" was given to that hypothetical homeostatic mechanism.