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A cytokine (for example, tumor necrosis factor-α, interleukin-6) produced by adipose tissue and acting locally in an autocrine-paracrine fashion or systemically as a hormone.
[adipo + G. kinēsis, movement]
Farlex Partner Medical Dictionary © Farlex 2012


A generic term for cytokines and other modulating proteins which are secreted by adipocytes. Some—e.g., IL-6—are pro-inflammatory,  whilst others—e.g., adiponectin—have anti-inflammatory or insulin-sensitising properties. Adipokine dysregulation appears to play a central role in adiposity, metabolic syndrome, and the co-morbidities of obesity including cardiovascular disease.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


, adipokine (ad″ĭ-pō-sīt′ŏ-kīn″) (ad′ĭ-pŏ-kīn″) [ adipo- + cytokine]
A molecule secreted by fat cells that affects the physiology of cells in other parts of the body. Some of these molecules influence appetite, the storage of fat in the body, and systemic inflammation.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
The patterns of altered levels of adipokine among obese subjects may be considered as important predictors for risk of colorectal cancer.
These findings support the hypothesis that, up from a certain point, an increase in fat mass changes the normal adipokine profile of the adipocytes and triggers metabolic dysfunction (2).
Serum levels of the adipokine vaspin in relation to metabolic and renal parameters.
Insulin use, adipokine profiles and breast cancer prognosis.
A recent meta--analysis (9) focused on adipokine profiles (ADIPOQ, LEP and RETN) as biomarkers in the gingival crevicular fluid (GCF) of obese and non-obese CP patients.
The authors also noted an increase in the values of anti-inflammatory adiponectin, an adipokine again connected with glucose maintenance and insulin sensitivity.
In addition to this basic function, lately adipose tissue was labelled an endocrine organ releasing hormones known as adipokine in the blood stream.6,7
Each PA parameter was related to inflammatory, endothelial, and adipokine markers extracted from fasting blood samples.
Keywords: [beta]-Glucan, Platycodin, db/db mouse, obesity, adipokine, composition.
Adipokine Levels and Perilipin Gene Polymorphisms in Obese Turkish Adolescents with Non-Alcoholic Fatty Liver Disease Erciyes Med J 2018; 40(2): 65-9.