adipokine

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ad·i·po·kine

(ad'i-pō-kīn),

A cytokine (for example, tumor necrosis factor-α, interleukin-6) produced by adipose tissue and acting locally in an autocrine-paracrine fashion or systemically as a hormone.

[adipo + G. kinēsis, movement]

Farlex Partner Medical Dictionary © Farlex 2012

Adipokine

A generic term for cytokines and other modulating proteins which are secreted by adipocytes. Some—e.g., IL-6—are pro-inflammatory, whilst others—e.g., adiponectin—have anti-inflammatory or insulin-sensitising properties. Adipokine dysregulation appears to play a central role in adiposity, metabolic syndrome, and the co-morbidities of obesity including cardiovascular disease.

adipocytokine

, adipokine (ad″ĭ-pō-sīt′ŏ-kīn″) (ad′ĭ-pŏ-kīn″) [ adipo- + cytokine]

A molecule secreted by fat cells that affects the physiology of cells in other parts of the body. Some of these molecules influence appetite, the storage of fat in the body, and systemic inflammation.

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References in periodicals archive ?

The patterns of altered levels of adipokine among obese subjects may be considered as important predictors for risk of colorectal cancer.

Association of Adipokines and Insulin, Which Have a Role in Obesity, with Colorectal Cancer

These findings support the hypothesis that, up from a certain point, an increase in fat mass changes the normal adipokine profile of the adipocytes and triggers metabolic dysfunction (2).

The Adipokine Profile and the Cardiometabolic Risk in Non-Obese Young Adults

Cord plasma lipid profile and adipokine levels of HPW and GDM newborns.

Adipokine levels and their association with insulin resistance and fetal outcomes among the newborns of Indian gestational diabetic mothers

Serum levels of the adipokine vaspin in relation to metabolic and renal parameters.

Is there a relationship between serum vaspin levels and insulin resistance in chronic renal failure?

Insulin use, adipokine profiles and breast cancer prognosis.

Adiponectin: A Predictor for Breast Cancer Survival?

A recent meta--analysis (9) focused on adipokine profiles (ADIPOQ, LEP and RETN) as biomarkers in the gingival crevicular fluid (GCF) of obese and non-obese CP patients.

Adipokine gene variability and plasma levels in patients with chronic periodontitis--a case--control study

The authors also noted an increase in the values of anti-inflammatory adiponectin, an adipokine again connected with glucose maintenance and insulin sensitivity.

Curcumin C3 Complex & BioPerine May Benefit Diabetics

In addition to this basic function, lately adipose tissue was labelled an endocrine organ releasing hormones known as adipokine in the blood stream.6,7

Association of Vaspin levels and its SNP rs2236242 with Gestational Diabetes at a tertiary care setting

Each PA parameter was related to inflammatory, endothelial, and adipokine markers extracted from fasting blood samples.

Cardiac Profiles Up With Exercise, Less Sitting in Early Old Age; Greater light, moderate-to-vigorous intensity activity tied to more favorable profile in adults age 60 to 64

Keywords: [beta]-Glucan, Platycodin, db/db mouse, obesity, adipokine, composition.

COMBINATION EFFECTS OF -GLUCAN ORIGINATED FROM AUREOBASIDIUM AND PLATYCODIN ON THE OBESE DB/DB MOUSE

Adipokine Levels and Perilipin Gene Polymorphisms in Obese Turkish Adolescents with Non-Alcoholic Fatty Liver Disease Erciyes Med J 2018; 40(2): 65-9.

Adipokine Levels and Perilipin Gene Polymorphisms in Obese Turkish Adolescents with Non-Alcoholic Fatty Liver Disease

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