adipokine

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ad·i·po·kine

(ad'i-pō-kīn),

A cytokine (for example, tumor necrosis factor-α, interleukin-6) produced by adipose tissue and acting locally in an autocrine-paracrine fashion or systemically as a hormone.

[adipo + G. kinēsis, movement]

Adipokine

A generic term for cytokines and other modulating proteins which are secreted by adipocytes. Some—e.g., IL-6—are pro-inflammatory, whilst others—e.g., adiponectin—have anti-inflammatory or insulin-sensitising properties. Adipokine dysregulation appears to play a central role in adiposity, metabolic syndrome, and the co-morbidities of obesity including cardiovascular disease.

adipocytokine

, adipokine (ad″ĭ-pō-sīt′ŏ-kīn″) (ad′ĭ-pŏ-kīn″) [ adipo- + cytokine]

A molecule secreted by fat cells that affects the physiology of cells in other parts of the body. Some of these molecules influence appetite, the storage of fat in the body, and systemic inflammation.

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References in periodicals archive ?

Visfatin, an adipokine, is a hormone, plasma levels of which are also associated with obesity, visceral fat, type 2 diabetes, and metabolic syndrome [48].

Histopathologic evaluation of nonalcoholic fatty liver disease in hypothyroidism-induced rats

Effects of tomato and soy on serum adipokine concentrations in postmenopausal women at increased breast cancer risk: a cross-over dietary intervention trial.

An anti-aging approach to cancer: harvest the protective potential of foods

Adiponectin is an adipokine produced exclusively by white adipose tissue (WAT) and plays an important role in obesity related morbidities like metabolic syndrome and cardiovascular disease (CVD).

SEX-DISCORDANT ASSOCIATION OF ADIPONECTIN IN OBESE AND NON-OBESE PRIMARY SCHOOL CHILDREN

Release of adiponectin, one of the marker adipokine was also decreased as indicated by ELISA results.

Oroxylin A, a constituent of Oroxylum indicum inhibits adipogenesis and induces apoptosis in 3T3-L1 cells

It also has been showing that circulating levels of this adipokine have a strong, direct correlation with hs-CRP as an acute phase protein [9].

Effects of resistance versus endurance training on plasma lipocalin-2 in young men

As an adipokine, circulating Lcn2 level has been reported to be increase in obese humans [14], and laboratory animals [16], than lean controls.

Effect of 8 weeks endurance training on plasma lipocalin-2 in overweight and obese men

glucose uptake, glucose production assays, expression of insulin-signaling cascade) together with assays that allow the monitoring of changes in adipokine and insulin secretion will improve our understanding of how pollutants can cause IR.

Insulin resistance and environmental pollutants: experimental evidence and future perspectives

Besides production of C3 in the liver, like other acute-phase proteins, C3 also synthesize by activated macrophages and adipocytes, therefore behaving as an inflammatory cytokine and adipokine.

Assessment of C-reactive protein and C3 as inflammatory markers of insulin resistance in women with polycystic ovary syndrome: a case-control study

Adiponectin is one of the most abundant adipokine and a protein hormone containing 244 amino acids.

RELATIONSHIP OF ADIPONECTIN LEVEL WITH GLYCEMIC STATUS AND LIPID PROFILE IN TYPE 2 DIABETIC MEN

Leptin is a pleiotropic adipokine and plays an important role in regulating appetite and body weight1.

ASSOCIATION OF PLASMA LEPTIN WITH CORONARY ARTERY CALCIUM (CAC) IN ADULTS

According to study published in the Scandinavian Journal of Medicine and Science in Sports, the researchers, including Rashmi Supriya from the Hong Kong Polytechnic University, one year of yoga training decreased pro-inflammatory adipokines-signalling proteins released by fat tissue-and increased an anti-inflammatory adipokine in adults with metabolic syndrome and high-normal blood pressure.

Yoga may benefit people suffering from BP, sugar: Study

According to study published in the Scandinavian Journal of Medicine and Science in Sports, the researchers, including Rashmi Supriya from the Hong Kong Polytechnic University, one year of yoga training decreased pro-inflammatory adipokines -- signalling proteins released by fat tissue -- and increased an anti-inflammatory adipokine in adults with metabolic syndrome and high-normal blood pressure.