The organization of adherens junctions
and desmosomes at the cardiac intercalated disc is independent of gap junctions.
This study examined the relationship between inflammatory cytokines (interleukin [IL]-6, tumor necrosis factor [TNF]-a, and IL-10) and adherens junctions
(E-cadherin, p120-catenin), which were ameliorated by glutamine in VILI, both in vitro and in vivo.
The previous concept of BBB is a pure endothelial barrier of the brain, a physical barrier comprised of tight junctions (TJs) and adherens junctions
(AJs) that limit paracellular diffusion of solutes between the blood and the brain [2, 3].
Our observations in monolayer culture of keratinocytes also fit this picture, with a clear membrane localization of C4.4A at cell-cell interaction points, suggesting a role of C4.4A in, for example, adherens junctions
. In addition, the carbohydrate-binding lectin galectin-3, which has been implicated in cell-cell interactions and cell adhesion, has been identified as a ligand for C4.4A .
Phosphorylation of the Drosophila adherens junction
protein Armadillo: roles for wingless signal and zeste-white 3 kinase.
In the results of pathway analysis, "Adherens junctions
" and "Focal adhesion" pathways were the two main types of junction that were modified by ISA adjuvants, which are known to mediate adhesion in epithelial cells (Yeatman, 2004).
[beta]- or [gamma]-catenin binds [alpha]-catenin to stabilize the adherens junction
anchorage to the actin cytoskeleton.
Several junctional complexes, including adherens junctions
and tight junctions, participate in this process .
Hammer et al., "Reduction and redistribution of gap and adherens junction
proteins after ischemia and reperfusion," Annals of Thoracic Surgery, vol.
Stimulation of ICAM-1 leads to phosphorylation of VE-cadherin, which is a prerequisite for adherens junction
Molecular components of the adherens junction
Additionally, the tight junction and adherens junction
pathways that play a role in the development of muscle contraction and structure were also regulated.