adenine

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adenine

 [ad´ĕ-nēn]
a purine base present in nucleoproteins of cells of plants and animals; adenine and guanine are essential components of nucleic acids. The end product of the metabolism of adenine in humans is uric acid. A preparation of adenine is used to improve the preservation of whole blood. Symbol A.
adenine arabinoside (ara-A) vidarabine.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ad·e·nine (A, Ade),

(ad'ĕ-nēn),
One of the two major purines (the other is guanine) found in both RNA and DNA, and also in various free nucleotides of importance to the body (for example, AMP (adenylic acid), ATP, NAD+, NADP+, and FAD); in all these smaller compounds, adenine is condensed with ribose at nitrogen-9, forming adenosine. For structure, see adenylic acid.
Synonym(s): 6-aminopurine
Farlex Partner Medical Dictionary © Farlex 2012

adenine

(ăd′n-ēn′, -ĭn)
n. Abbr. A
A purine base, C5H5N5, that is the constituent involved in base pairing with thymine in DNA and with uracil in RNA.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

Adenine

One of 2 (the other is thymine) major purine bases (C5H5N5) in nucleic acid. Adenine pairs with a pyrimidine in nucleic acids—with thymine in DNA, or with uracil in RNA; adenine combines with deoxyribose to form deoxyadenosine in DNA and ribose to form adenosine in RNA. Adenine is a major factor in a plethora of biological and molecular reactions.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

ad·e·nine

(A, Ade) (ad'ĕ-nēn)
One of the two major purines (the other being guanine) found in both RNA and DNA, and also in various free nucleotides.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

adenine

A purine base. One of the four key biochemical units from which genes are formed in DNA and by which the two helical halves of the DNA molecule are linked together. Adenine pairs with thymine in DNA, but in RNA it pairs with uracil.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
Adenineclick for a larger image
Fig. 14 Adenine . Complementary pairing. P = phosphate group.
Adenineclick for a larger image
Fig. 13 Adenine . Molecular structure.

adenine (A)

one of four types of nitrogenous bases found in DNA, having the double-ring structure of a class known as PURINES (see Fig. 13 ).

Adenine forms part of a DNA unit called a NUCLEOTIDE and always forms COMPLEMENTARY BASE PAIRING with a DNA PYRIMIDINE base called THYMINE (see Fig. 14 ). When pairing with RNA during TRANSCRIPTION, adenine is complementary to URACIL. Adenine also occurs in RNA molecules, ATP, ADP and AMP.

Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

ad·e·nine

(ad'ĕ-nēn)
A purine found in both RNA and DNA, and also in various free nucleotides of importance to the body.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Bagatini et al., "Activities of the enzymes that hydrolyze adenine nucleotides in platelets from multiple sclerosis patients," Journal of Neurology, vol.
Methods for the determination of adenosine triphosphate and other adenine nucleotides. J.
Chen, "Adenine nucleotide translocase, mitochondrial stress, and degenerative cell death," Oxidative Medicine and Cellular Longevity, vol.
The Kinetics of the Extracellular Catabolism of Adenine Nucleotides (ATP and ADP) Was Not Different in Control and Postinflammation Preparations of the Rat Ileum.
Battastini, "Neonatal hypothyroidism affects the adenine nucleotides metabolism in astrocyte cultures from rat brain," Neurochemical Research, vol.
The steady-state levels of ADP and ATP reflect well-known diffusion restrictions for adenine nucleotides (see for review Vendelin et al., 2004, 2007) for passing through the mitochondrial porin channel (VDAC) as well the absence of these restrictions for PCr--which should reach the cellular cytoplasm.
Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5'-nucleotidase-mediated conversion of adenine nucleotides. J Clin Invest.
Adenine nucleotide release from isolated perfused guinea pig hearts and extracellular formation of adenosine.
Purine salvage to adenine nucleotides in different skeletal muscle fiber types.
Typically, phosphagen concentrations are higher than adenine nucleotide concentrations (Beis and Newsholme, 1975; Meyer et al., 1984).
These reactions lead to catabolic end-products that are washed out of the cell with a subsequent loss in purines and adenine nucleotides. One therapeutic option is to try to restore these energy substrates in order to recover the function of the cell, including muscle cells.