adaptive immunity


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Adaptive Immunity

Immunity mediated by CD4+ helper T lymphocytes and CD8+ cytotoxic T lymphocytes (CTLs), which distinguish themselves from innate immune cells by expressing antigen-specific receptors formed by gene rearrangements, which allows a more flexible and broader repertoire of responses than is possible with innate immune cells, which express germline-encoded receptors

adaptive immunity

The component of immunity that is pathogen-specific and creates memory. It consists of the mechanisms of cell-mediated and antibody-mediated immunity.
See: innate immunity
See also: immunity
References in periodicals archive ?
Adaptive immunity is highly specific to particular pathogens and can be either temporarily borrowed from an artificial source (passive immunity) or can be permanently acquired through the body's own immunological memory (active immunity).
Since there were many similarities in the pathological progress of obesity and T2DM, which are tightly linked, altered proliferation, function, or infiltration of components of adaptive immunity and innate immunity is critical in the progression of T2DM.
The role of mammalian antimicrobial peptides and proteins in awakening of innate host defenses and adaptive immunity. Cell Mol Life Sci 2001;58:978-89.
[13] Gasiunas, G., et al., Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria.
A unique feature of the adaptive immunity is its ability to generate and to retain memory providing a more rapid response in the event of subsequent immunologic challenge.
Innate immunity: The host immunity is divided into innate and adaptive immunity. The innate immunity is also termed as non-specific immunity, which acts as first line of bastille against infectious agents like intracellular bacteria (e.g.
This group found that mice deficient in FLG developed a skin inflammation analogous to AD (and driven by innate immunity), then later developed compromised lung function (a process resulting from adaptive immunity).
Sympathetic hearing loss (SHL), also known as sympathetic cochleolabyrinthitis, is a rare phenomenon of immune-related hearing loss that is believed to occur when adaptive immunity develops due to exposure of sequestered inner ear antigens to the surrounding circulatory milieu.
The Authors nicely and concisely illustrate (a) the effects of selected vanadium species in the immune system processes, (b) forms of vanadium exhibiting immunogenic activity, and (c) the key role(s) of vanadium in promoting innate and adaptive immunity as well as (d) current obstacles to be overcome by specifically designed vanadium metallodrugs in cancer immunotherapeutics.
Immunology:Complement system, Innate and adaptive immunity, clinical immunology, Basic principles and application of immunological and serological techniques.
Consequently, tumor cells are eliminated by adaptive immunity through the activation of cytotoxic CD[8.sup.+] T-cells and NK-cells, and by innate immunity through the activation of antitumor macrophages (M1 subtype), antitumor neutrophils (N1 subtype), and granulocytes [3].
The adaptive immunity, on the other hand, is more of an antigen-specific response, triggered only when the innate immune system has failed to overwhelm the infection.

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