dapsone

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dapsone

 [dap´sōn]
an antibacterial used in treatment of leprosy and dermatitis herpetiformis and for prophylaxis of malaria caused by Plasmodium falciparum. Called also DDS.

dap·sone

(dap'sōn),
An antibiotic used to treat leprosy and certain cutaneous diseases such as dermatitis herpetiformis, is active against the tubercle bacillus, is used in the treatment of bovine coccidiosis and streptococcal mastitis, and is used as a second-line agent in Pneumocystis jiroveci [carinii] pneumonia.

dapsone

/dap·sone/ (dap´sōn) an antibacterial bacteriostatic for a broad spectrum of gram-positive and gram-negative organisms; used as a leprostatic, as a dermatitis herpetiformis suppressant, and in the prophylaxis of falciparum malaria.

dapsone

(dăp′sōn′, -zōn′)
n.
A sulfone drug, C12H12N2O2S, that is used primarily to treat leprosy and some forms of dermatitis.

dapsone (DDS)

[dap′sōn]
a bacteriostatic and bactericidal sulfone derivative.
indications It is prescribed in the treatment of leprosy and dermatitis herpetiformis and for prophylaxis against toxoplasmosis and Pneumocystis carinii in immunocompromised patients.
contraindications Known hypersensitivity to this drug prohibits its use. It is not recommended for use during pregnancy or lactation.
adverse effects Among the more serious adverse reactions are hemolysis (particularly in people who have glucose-6-phosphate dehydrogenase deficiency), leprosy reactional state, methemoglobinemia, neuropathy, nausea, anorexia, toxic hepatic aplastic anemia, and skin rash. Dapsone was carcinogenic in animal models.

dap·sone

(dap'sōn)
An antibiotic used to treat leprosy and cutaneous diseases such as dermatitis herpetiformis; active against the tubercle bacillus; used in the treatment of bovine coccidiosis and streptococcal mastitis and as a second-line agent in Pneumocystis jiroveci [carinii] pneumonia.

dapsone

Diaminodiphenyl sulfone. For many years this has been the standard drug to treat leprosy, but irregular use has led to the development of drug resistance. Dapsone is also used in the treatment of DERMATITIS HERPETIFORMIS which may be associated with COELIAC DISEASE.

dap·sone

(dap'sōn)
Antibiotic used to treat leprosy; active against the tubercle bacillus; used as a second-line agent in Pneumocystis jiroveci (carinii) pneumonia.

dapsone (DDS)

(dap´sōn),
n brand name: Avlosulfon;
drug class: leprostatic, antibacterial;
action: bactericidal and bacteriostatic against
M. leprae; may also be immunosuppressant;
uses: leprosy and dermatitis herpetiformis.

dapsone

an antibacterial used in humans for the treatment of leprosy and malaria. Used in cats to treat mycobacterial infections, particularly feline leprosy, caused by Mycobacterium lepraemurium.
References in periodicals archive ?
ACZONE Gel is a topical formulation of dapsone that is used to treat acne in patients 12 years of age and older.
Comment: Efficacy was based on two clinical studies that compared Aczone Gel, 5% and vehicle in a total of 3,000 patients 12 years and older.
She recommends starting out slowly with Aczone to monitor response.
He is a consultant to Galderma, which markets MetroGel, but is not involved in the Aczone trials.
We are excited to make Aczone Gel 5% widely available to dermatologists and their patients in North America.
Aczone is indicated for the treatment of acne vulgaris in the United States and Canada in patients ages 12 and olden It is the only acne treatment harnessing dapsone in a topical formulation to provide a convenient and effective therapy, says a company spokesman.
Aczone and Atrigel are both registered trademarks of QLT USA, Inc.