acute phase protein

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acute phase protein

plasma proteins associated with inflammation including C-reactive protein (CRP), mannose-binding protein, serum amyloid P component, α1-antitrypsin, fibrinogen, ceruloplasmin, and complement components C9 and factor B, the concentrations of which increase in response to interleukins 1, 6, and 11.

acute phase protein

Any of the plasma proteins whose concentration increases or decreases by at least 25% during inflammation. Acute-phase proteins include C-reactive protein, several complement and coagulation factors, transport proteins, amyloid, and antiprotease enzymes. They help mediate both positive and negative effects of acute and chronic inflammation, including chemotaxis, phagocytosis, protection against oxygen radicals, and tissue repair. In clinical medicine the erythrocyte sedimentation rate or serum C-reactive protein level sometimes is used as a marker of increased amounts of acute-phase proteins. Synonym: acute phase reactant See: inflammation
See also: protein
References in periodicals archive ?
The gains came despite Chinese stock markets sputtering, although other equity markets across the Asia-Pacific region performed better, continuing the recouperation from last week's acute phase of risk-off positioning.
"Evidence shows that rapid specialist assessment and intervention in the hyper acute phase (the first 72 hours after a stroke) reduces mortality and improves long term outcomes for stroke patients with reduced disability and dependency on health and social care services.
The acute phase response (APR) is an early, non-specific systemic innate immune reaction to local or systemic stimulus, which helps to heal and re-establish homeostasis and minimize tissue damage when the body is affected by trauma, infection, stress, surgery, neoplasia or inflammation (GRUYS et al., 2005; CRAY et al., 2009; ECKERSALL & BELL, 2010).
Laboratory findings were as follows: white blood cell count: 13,470/[mm.sup.3], acute phase reactants (erythrocyte sedimentation rate: 26 mm/h, C-reactive protein: 37 mg/L) and antistreptolysin-O titer: 1270 IU/mL (increased).
Results: Serum S100B [(0.59 +- 0.11) ng/ml] and GFAP [(227.67 +- 12.43) ng/ml] levels of DEACMP group in acute phase were significantly higher than those of ACMP group [(0.48 +- 0.10) ng/ml and (178.91 +- 11.47) ng/ml] and DEACMP group in recovery phase [(0.49 +- 0.12) ng/ml and (179.54 +- 12.32) ng/ml] (all P<0.05).
Little is known about the level and correlates of uncertainty among patients in the acute phase of stroke.
The intended audience includes all practitioners who care for patients in the acute phase of stroke care, from emergency medical dispatchers, fire chiefs, emergency medical services providers, emergency physicians and nurses, neurology and neurocritical care providers and nurses, stroke coordinators, and neurointerventionalists.
Systemic infection is currently irreversible after the onset of the acute phase. Preventing systemic hiv infection after exposure, Therefore, Requires understanding and targeting the eclipse phase.
Acticor Biotech is company developing an antithrombotic agent for the treatment of the acute phase of ischemic stroke.
These abnormalities may persist even after the acute phase without the involvement of the coronary arteries [2].
Damage due to burn or trauma, surgical procedures, advanced malignancies, immunologically and inflammatory disorders, and so on are some of the common stimuli which can induce a complex and defensive biological mechanism of the body called acute phase response (APR).
But, she continued, these symptoms are of the acute phase of the diseases.

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