acute phase protein

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acute phase protein

plasma proteins associated with inflammation including C-reactive protein (CRP), mannose-binding protein, serum amyloid P component, α1-antitrypsin, fibrinogen, ceruloplasmin, and complement components C9 and factor B, the concentrations of which increase in response to interleukins 1, 6, and 11.

acute phase protein

Any of the plasma proteins whose concentration increases or decreases by at least 25% during inflammation. Acute-phase proteins include C-reactive protein, several complement and coagulation factors, transport proteins, amyloid, and antiprotease enzymes. They help mediate both positive and negative effects of acute and chronic inflammation, including chemotaxis, phagocytosis, protection against oxygen radicals, and tissue repair. In clinical medicine the erythrocyte sedimentation rate or serum C-reactive protein level sometimes is used as a marker of increased amounts of acute-phase proteins. Synonym: acute phase reactant See: inflammation
See also: protein
References in periodicals archive ?
First, None of these models reconcile the very small per-exposure hiv-1 acquisition probability with the high estimate of the basic reproductive number, R0, During acute phase infection.
But, she continued, these symptoms are of the acute phase of the diseases.
On admission to our hospital acute phase reactants; erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), fibrinogen and white blood cell (WBC) were high.
Objective: To analyze the acute phase reactants in patients suffering from rheumatoid arthritis (RA) and compare them to healthy controls.
Hepcidin (Hep), ferroportin-1(Fpn-1) and transferrin (Tf) are the important proteins associated with iron metabolism and the onset of acute phase response (APR) influences their gene expressions.
Zika virus is closely related to dengue virus, and during the acute phase of disease, Zika virus might release NS1 into patients' serum; however, this putatively released nonstructural protein does not appear to cross-react with the dengue NS1 tests used in our study.
In recent times, significant attention has been paid to the study of acute phase reactants in patients with Chronic Renal Failure (CRF) undergoing haemodialysis.
The company stated that SUSTOL's efficacy in preventing nausea and vomiting was evaluated in both the acute phase (day one following chemotherapy) and the delayed phase (days two-five following chemotherapy), concluded the company.
So the Philhealth might cover the two-week acute phase,' Ubial said.
Nonspecific components of the immune system, acute phase proteins (APPs) inhibit the continuity of tissue damage, isolating and destroying the pathogenic agent and activating the process of tissue repair necessary for returning to normality (MURATA et al.
Because captive flamingos often suffer from pododermatitis, feet of all flamingos were scored to determine whether pododermatitis would be reflected in the acute phase proteins.

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