Acute Silicosis

Acute Silicosis

A complication of intense exposure to respirable crystalline silica, associated with sandblasting, coal mining, or any other job in which there is heavy exposure to fine particulate silica. Unlike classic silicosis, acute silicosis appears within a few weeks to 5 years of initial exposure. 
Occupations Abrasive (sand) blasting, mining, quarrying, manufacture of abrasives—including abrasive soaps, tunnelling, foundry work, glass manufacture, ceramic and pottery production, and cement and concrete production.
Clinical findings Rapid onset of severe respiratory impairment, dyspnoea, cough, weakness, weight loss, often leading to death.
Imaging, chest Multifocal ground glass appearance and air space consolidation.
DiffDx Pneumonia, pulmonary oedema, alveolar haemorrhage, bronchioloalveolar cell cancer.
References in periodicals archive ?
Because apoptosis is believed to play an essential role in the inflammation associated with one pneumoconiosis, acute silicosis, and because inflammation increased as CYP1A1 activity decreased in the rat model of coal workers' pneumoconiosis (Ghanem et al.
But acute silicosis can occur after only a few months of extremely high concentrations of respirable silica.
Sand blasters, rock drillers, and silica-flour millers all face a high risk of acute silicosis, a life-threatening inflammatory disease that disables its victims--sometimes in as little as 5 years--by killing lung cells and letting their liquids leak out.

Full browser ?