Acute Leukaemia


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Acute Leukaemia

A rapidly progressive malignancy of sudden onset, which is characterised by an uncontrolled clonal proliferation of immature white cells, which replace bone marrow and spill into the peripheral blood.
Clinical findings, acute lymphocytic leukaemia Generalised malaise and fatigue, anaemia, fever, weight loss, anorexia, bruising, bone and joint pain, dyspnoea, increased infections.
Clinical findings, acute myeloid leukaemia Generalised malaise and fatigue, anaemia, fever, weight loss, anorexia, bruising, petechiae, bone and joint pain, dyspnoea, increased infections.
Lab Pancytopaenia with circulating blasts, hyperuricaemia. 
Prognosis Untreated acute leukaemia may be fatal in weeks to months.
References in periodicals archive ?
Re-evaluation of the periodic acid Schiff stain in acute leukaemia with immunophenotypic analyses.
Risk factors for acute leukaemia in children: a review.
Immunophenotyping of the patients suspected to have acute leukaemia was done.
Conclusion: Acute leukaemias were more prevalent than chronic leukaemias.
Morphologically if a case of acute leukaemia has the cytological feature of ALL-L1 then it is highly likely that it does represent ALL (6).
Washington, Nov 14 (ANI): If patients with acute leukaemia are transplanted with two units of umbilical cord blood (UCB), their risk of the disease recurrence is significantly reduced, according to a new study from the Masonic Cancer Center, University of Minnesota.
This was the question brave teenager Zakk Hutton asked doctors after being told he had acute leukaemia.
Elacyt is a novel cytotoxic agent, an analogue of cytarabine, a backbone of therapy in acute leukaemia. It is in development for the treatment of haematological cancers as well as for solid tumours.
[4.] Gunz FW, Spears GFS: Distribution of acute leukaemia in time and space.
hypoplastic/ fibrotic marrow in aplastic anaemia, marrow necrosis in myelodysplastic syndrome, acute leukaemia and hairy cell leukaemia, dry tap in myelofibrosis, granulomas in granulomatous diseases like tuberculosis and brucellosis.
Acute leukaemia, where the symptoms tend to develop rapidly, and chronic leukaemia, where symptoms may take some years to develop.
The 37-year-old retired from professional football in 2013 after being diagnosed with acute leukaemia the year before.

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