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SC Soluble Insulin (actrapid)###Anti-diabetic###14 units TDS
Actrapid was not transferred through the milk as no sign of hypoglycemia could be detected in the offspring (Figure 7(a)).
Collagenase (Collagenase NB 4 Standard Grade from Clostridium histolyticum) was obtained from SERVA Electrophoresis GmbH (Heidelberg, Germany), insulin and glucagon (Actrapid, Novo Nordisk A/S, Bagsvaerd, Denmark) and prednisolon (Merck KGaA, Darmstadt, Germany) were from the suppliers mentioned in brackets.
Subjects received continuous 5-hour infusion ofinsulin (Actrapid, 100 IU/mL; Novo Nordisk, Bagsvaerd, Denmark) at 0.05 U * [min.sup.-1] [m.sup.-2].
All three groups, the normal mice, the mice with type 1 DM, and the mice with type 2 DM, were intraperitoneally injected with borapetoside A, Actrapid or metformin.
Each subject was given a 150-minute intravenous infusion of somatostatin (270 [micro]g/h; Somatosan, Wasserburger Arzneimittelwerk GmbH, Wasserburg, Germany), insulin (0.4mU/kg/min; Actrapid HM, Novo Nordisk, Denmark), and glucose (6 mg/kg/min; in a 20% solution).
Imipenem (0.5 g, Tienam, Merck Sharp & Dohme, Sollentuna, Sweden), insulin (20 IU, Actrapid, Novo Nordisk, Bagsvaerd, Denmark), and heparin (10,000 IU, Leo Pharma, Malmo, Sweden) were added, and isotonic trometamol (Addex-THAM, Kabi, Sweden) was used to buffer the mixed solution to a temperature-adjusted pH of 7.4.
Human insulin (Actrapid, Novo Nordisk, Bagsvaerd, Denmark) was infused at a constant rate based on lean body mass estimated according to  via a dedicated jugular vein catheter using a syringe pump (CMA1100, Carnegie Medicin, Solna, Sweden).
Neutral insulin (Actrapid and Humulin R) is a short-acting recombinant human insulin.
Insulin (Actrapid HM, Novo Nordisk, Denmark) was given intravenously via central vein rout using a 50 ml syringe and standard infusion pump (Perfussor-FM pump, B braun).
Table 1 Insulin sliding scale infusion 50 units of Actrapid insulin in 50 ml of 0.9% saline should be infused at a rate adjusted according to the infusion table below.
Brands and the prices in the UAE market for that day were: $14.84 (Dh55) for Humulin R of Eli Lilly, $17.02 (Dh63) for Actrapid HM of Novo Nordisk and $12.39 (Dh46) for Jusline R of Julphar.
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