pure red cell aplasia
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pure red cell a·pla·si·a
a transitory arrest of red blood cell production that may occur in the course of a hemolytic anemia, often preceded by infection, or as a complication of certain drugs; if the arrest persists, severe anemia may result.
See also: congenital hypoplastic anemia.
See also: congenital hypoplastic anemia.
Farlex Partner Medical Dictionary © Farlex 2012
pure red cell aplasia
Hematology A type of anemia caused by selective depletion of erythroid cells Pure red cell aplasia types
Acute Aplastic crisis A condition often preceded by viral gastroenteritis, pneumonitis, primary atypical pneumonia, mumps, viral hepatitis, pregnancy and drug toxicity Clinical Malaise, pallor and other symptoms of a chronic, compensated hemolyzing process Treatment The only effective modality is discontinuance of inculpated drug, if identified
Chronic Either
.1.Congenital Diamond-Blackfan disease A condition due to a ↓ in erythrocyte stem cells with ↓ colony-forming units and burst-forming units and a poor response to erythropoietin Treatment Transfusions, corticosteroids or.
2. Acquired 30-50% of chronic acquired PRCA is associated with thymoma, as well as rheumatoid arthritis, lupus erythematosus, chronic active hepatitis, hemolytic anemia and CLL
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
pure red cell aplasia
A severe failure of production of red blood cells by the bone marrow with normal production of other blood cells. The result is a temporary or persistent severe anaemia. The condition may be caused by some virus infections, some drugs, cancers, rheumatoid arthritis and systemic lupus erythematosus.Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005