pure red cell aplasia

pure red cell a·pla·si·a

a transitory arrest of red blood cell production that may occur in the course of a hemolytic anemia, often preceded by infection, or as a complication of certain drugs; if the arrest persists, severe anemia may result.
See also: congenital hypoplastic anemia.

pure red cell aplasia

Hematology A type of anemia caused by selective depletion of erythroid cells

Pure red cell aplasia types

Acute Aplastic crisis A condition often preceded by viral gastroenteritis, pneumonitis, primary atypical pneumonia, mumps, viral hepatitis, pregnancy and drug toxicity Clinical Malaise, pallor and other symptoms of a chronic, compensated hemolyzing process Treatment The only effective modality is discontinuance of inculpated drug, if identified

Chronic Either

1.Congenital Diamond-Blackfan disease A condition due to a ↓ in erythrocyte stem cells with ↓ colony-forming units and burst-forming units and a poor response to erythropoietin Treatment Transfusions, corticosteroids or.

2. Acquired 30-50% of chronic acquired PRCA is associated with thymoma, as well as rheumatoid arthritis, lupus erythematosus, chronic active hepatitis, hemolytic anemia and CLL  

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pure red cell aplasia

A severe failure of production of red blood cells by the bone marrow with normal production of other blood cells. The result is a temporary or persistent severe anaemia. The condition may be caused by some virus infections, some drugs, cancers, rheumatoid arthritis and systemic lupus erythematosus.

aplasia

defective development or complete absence of an organ or tissue due to failure of development.

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aplasia cutis

see epitheliogenesis imperfecta.

pure red cell aplasia

selective depression of erythropoiesis with anemia resulting.

segmental aplasia

aplasia of a segment of an organ, e.g. uterus.