can appear clinically similar to ichthyosis vulgaris.
The association of hypothyroidism and acquired ichthyosis
may be due to the role of thyroid hormone in fatty acid metabolism and sterol production in the skin.
Acquired ichthyosis can be associated with medications, malignancies, and autoimmune, infectious, neurological, nutritional, endocrine, and metabolic diseases (1, 2).
Beware of underlying malignancy: acquired ichthyosis. Am J Med.
(3-5) We report a patient having generalised painful/ tender lymphadenopathy and acquired ichthyosis
who was initially diagnosed with TB Lymphadenitis, then Hodgkin's lymphoma but later was found to have lepromatous leprosy and Type II Lepra reaction.
* Acquired Ichthyosis. Extremely dry, scaly skin is a characteristic feature of this condition.
It is very similar to ichthyosis vulgaris, but unlike the genetic forms, acquired ichthyosis tends to spare the palms of the hands and soles of the feet.
Nonspecific skin changes seen in 9 (9%) cases, in which commonest was acquired ichthyosis
, 3 (3%) seen in carcinoma oesophagus, 2 (2%) in carcinoma stomach and 1 (1%) in non-Hodgkin's lymphoma.
Koilonychia, paronychia, lichen planus, acquired ichthyosis
and shiny nails were present in 5.6% of the patients.
was present in 2 (15.3%) cases.
The xerosis was severe in some cases to be considered as an acquired ichthyosis
. Hypohidrosis accompanied by cytologic changes within the eccrine apparatus and diminished sebaceous gland secretion are considered potential etiological factors.
Based on the history, clinical examination and histological findings a diagnosis of acquired ichthyosis