SMPD1(redirected from Acid sphingomyelinase sphingomyelin phosphodiesterase)
SMPD1A gene on chromosome 11p15.4-p15.1 that encodes a lysosomal acid sphingomyelinase, which converts sphingomyelin to ceramide and has phospholipase C activity.
SMPD1 mutations are linked to Niemann-Pick disease types A and B.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.