Action of Acetyl-L-Carnitine
in Neurodegeneration and Alzheimer's Disease.
NUTRIENTS TO COMBAT ALZHEIMER'S DISEASE Nutrients with Strong Evidence from Human Studies Acetyl-L-carnitine
Lipoic acid Panax ginseng N-acetyl cysteine (NAC) Huperzine A Omega-3 fatty acids Vitamin D Ginkgo biloba Nutrients with Strong Evidence from Epidemiological Studies Coffee Vitamin E Magnesium Nutrients with Strong Laboratory and Theoretical Evidence B vitamins Blueberry extracts CoQ10 PQQ Curcumin Grape seed extract Green tea Resveratrol Vinpocetine Ashwagandha LE: Are there any dietary or lifestyle strategies to reduce the risk of Alzheimer's?
supplementation restores decreased tissue carnitine levels and impaired lipid metabolism in aged rats.
An animal dementia model was established and the effect of acetyl-L-carnitine
on cognitive deficit was examined with the dementia model.
administration increases phosphor-Thr34 DARPP-32 levels and antagonizes cocaine-induced increase in Cdk5 and phosphor-Thr75 DARPP-32 levels in rat striatum.
If you buy ALCAR alone, be sure the label says acetyl-L-carnitine
and not just plain L-carnitine.
The dietary supplement acetyl-L-carnitine
may help improve mental function in older adults, according to a study published in the December 2007 issue of The American Journal of Clinical Nutrition.
. This dietary supplement appeared to reduce MS patients' fatigue severity, and no such effect was seen with the more standard MS fatigue medication amantadine in a small study.
The pills also contained a building block for glutathione, an antioxidant made by the body; acetyl-L-carnitine
; and S-adenosyl methionine.
The authors suggested that the suppressed platelet activity was caused by intracellular hydrolysis of propionyl-L-carnitine to L-carnitine with subsequent depletion of acetyl-CoA as a result of acetyl-L-carnitine
In HIV+ patients with this condition, blood levels of a natural substance called acetyl-L-carnitine
(ALCAR) tend to be lower.
Carnitine (also known as L-carnitine and acetyl-L-carnitine
) is an amino acid that is made in the liver and kidneys, it is also found in meat and dairy products, (25) but there is very little found in plant foods.