Acetyl-l-Carnitine


Also found in: Acronyms.

Acetyl-l-Carnitine

Alternative A form of carnitine which may metabolise lipofuscin and age-related pigment deposits; it is claimed to attenuate age-associated memory loss and Alzheimer’s disease, and increase longevity.
Source Meats—beef, chicken, pork—dairy products, fruits, vegetables, grains
Physiology An acetylated metabolic byproduct of l-carnitine and acetyl-CoA, which is produced within mitochondria during strenuous exercise. ALCAR is a potent antioxidant and nutrient which helps transport fatty acids across lipid membranes into mitochondria, rejuvenating membranes and effete enzymes.
References in periodicals archive ?
Those cited in this paper include Saffron, Omani fruits, Omega-3 fatty acids, curcumin, glutathione, Acetyl-L-carnitine, Alpha-lipoic acid, B vitamins, Ginkgo Biloba, flavonoids, polyphenols, DMAE among others.
Acetyl-L-carnitine supplementation restores decreased tissue carnitine levels and impaired lipid metabolism in aged rats.
An animal dementia model was established and the effect of acetyl-L-carnitine on cognitive deficit was examined with the dementia model.
Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism.
Psychosis precipitated by acetyl-L-carnitine in a patient with bipolar disorder.
If you buy ALCAR alone, be sure the label says acetyl-L-carnitine and not just plain L-carnitine.
2002, Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress, PNAS, 19: 4, 1870-5.
In addition, he's created a combination of specific brain supporting nutrients, including acetyl-L-carnitine, alpha lipoic acid, coenzyme Q10, n-acetyl-cysteine, and phosphatidylserine.
Levels of carnitines in brain and other tissues of rats of different ages: effect of acetyl-L-carnitine administration.
The dietary supplement acetyl-L-carnitine may help improve mental function in older adults, according to a study published in the December 2007 issue of The American Journal of Clinical Nutrition.
In a study by Tomassini et al, (9) acetyl-L-carnitine reduced fatigue in multiple patients compared with amantadine.
The authors suggested that the suppressed platelet activity was caused by intracellular hydrolysis of propionyl-L-carnitine to L-carnitine with subsequent depletion of acetyl-CoA as a result of acetyl-L-carnitine formation (13).