thiolase

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a·ce·tyl-CoA a·ce·tyl·trans·fer·ase

an acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis.

Synonym(s): acetoacetyl-CoA thiolase, acetyl-CoA thiolase, thiolase

thiolase

An obsolete generic term for any enzyme (e.g., acetyl CoA acetyltransferase [EC 2.3.1.9]) which catalyses a reaction between a compound, R–R’, and a thiol, R’–SH, forming R–S–R’ and R'–H.

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References in periodicals archive ?

The expression levels of 3-hydroxyacyl-CoA dehydrogenase type-2 (HCDH), acetyl-Coenzyme A acetyltransferase 2 (ACAT) and elongation factor Tu were down-regulated, and alpha-enolase and creatine kinase were up-regulated in the livers of ketotic cows.

Acetyl-Coenzyme A acetyltransferase 2 (ACAT) transforms acetyl-CoA into acetoacetyl-CoA and can increases the rate of ketogenesis.

Metabolic characteristic of the liver of dairy cows during ketosis based on comparative proteomics