The antithrombotic therapy included warfarin and acenocoumarol
within control groups, (19) and patients with modified therapy received therapy bridge (nadroparin calcium), (13) decreased dose of antithrombotic agent, or therapy suspension.
was also started at a dose of 2mg daily.
Treatment was consisting in low molecular weight heparin for a week associated with adjusting dose of acenocoumarol
A case study of acenocoumarol
sensitivity and genotype-phenotype discordancy explained by combinations of polymorphisms in VKORC1 and CYP2C9.
This was demonstrated in a cohort of 112 Dutch patients treated with acenocoumarol
who received an NSAID (diclofenac, naproxen, or ibuprofen).
2,3) We studied the outcomes in patients treated with acenocoumarol
for more than 6 months in a series of consecutive outpatients with VTD from a rural Spanish area.
11) An open-label, randomized noninferiority study (EINSTEIN) compared rivaroxaban (15 mg twice daily for 3 weeks followed by 20 mg daily for 3, 6, or 12 months) to the low-molecular-weight heparin enoxaparin (1 mg/kg body weight, dosed twice daily) followed by either warfarin or acenocoumarol
(to achieve an INR of 2-3) for patients with acute, symptomatic DVT.
Judes mechanical valve after taking excess of acenocoumarol
for 4 days, (total dose 24mg) presented with two day history of sudden onset rapidly progressive weakness in right lower limb followed by left lower limb in a day with urinary retention and constipation.
5-5 mg twice a day, and triflusal 600 mg plus acenocoumarol
to reach an INR target of 1.
His fever subsided, and he was discharged a few days later while continuing to receive acenocoumarol
, an oral coumarin anticoagulant.
5 mg/wk and 2,293 to oral adjusted-dose vitamin K antagonists (warfarin or acenocoumarol
, target international normalized ratio of 2.
Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol