vera such as acemannans
, glucomannans, aloctin A, and aloe emodin (Hu et al., 2003; Akev et al., 2015).
Gonzalez-Laredo et al., "Effects of pasteurization on bioactive polysaccharide acemannan
and cell wall polymers from Aloe barbadensis Miller," Carbohydrate Polymers, vol.
Yun et al., "Acemannan
purified from Aloe vera induces phenotypic and functional maturation of immature dendritic cells," International Immunopharmacology, vol.
Femenia, "Effect of different drying procedures on the bioactive polysaccharide acemannan
from Aloe vera (Aloe barbadensis Miller)," Carbohydrate Polymers, vol.
The reason for higher monocyte count may be attributed to the presence of mannose polysaccharide (acemannan
) which binds with mannose receptor on monocyte and stimulates production of various cytokines like IL-1, IL-6, IL-12 and TNF- [+ or -].
vera is a rich source of many carbohydrate units including polysaccharide, mannose-6- phosphate and acemannan
(mannose-6-phosphate) fits the growth factor receptors on the surface of the fibroblasts, enhancing their activity, stimulating fibroblast-cells which produce collagen fibers to strengthen the new tissue formation that heal wounds.
The effect of Acemannan
immunostimulant in combination with surgery and radiation therapy on Spontaneous canine and Feline fibrosarcomas.
stimulates the synthesis and release of interleukin-1 (IL-1) and tumor necrosis factor from macrophages which in turn initiates an immune attack that result in necrosis and regression of the cancerous cells.