Immunomodulatory potential of acemannan
(polysaccharide from Aloe vera) against radiation induced mortality in Swiss albino mice.
Major polysaccharides containing Mannose named Acemannan
has been isolated by various researchers (Hart et al.
It has been reported that acemannan
hydrogel accelerates the healing of aphthous ulcers and reduces the pain associated with them.
The main objective of this work was to set up a protocol for callus induction and plant regeneration through indirect somatic embryogenesis (ISE) by studying the influence of plant growth regulators and explant source; and, to compare the acemannan
content in the inner gel of fresh leaves with the one from embryogenic calluses.
Carrington is a research-based biopharmaceutical company currently utilizing naturally-occurring polysaccharides to produce Acemannan
Immunostimulant, an injectable biologic for the treatment of fibrosarcoma in cats and dogs; Acemannan
Hydrogel used in products for radiation dermatitis, and other wound and oral care applications; and a variety of polysaccharide raw materials for use in dietary supplement formulations.
Zim's Advanced Gel with Acemannan
will be available in a 3-ounce version, while Zim's Advanced with Hydrocortisone will be available both in a 3-ounce cream and a 3.
We administered leaf skin and pulp extract components derived from a phenol low molecular weight component, a glycoprotein component and a carboxypeptidase fraction derived from Kidachi aloe to mice to compare the inhibitory effects on the Sz-induced enhancement of vascular permeability so that we can search any component participated in other action mechanisms to protect pancreatic islet B cells than the hypoglycemic action shown by glucans, Acemannan
or other polysaccharides.
An evaluation of the synergistic antiviral effects of acemannan
in combination with azidothymidine and acyclovir.
Carrington currently holds approximately 120 patents, issued and pending, in 26 countries under which it manufactures its drug product Aliminase currently in Phase III clinical trials for the treatment of ulcerative colitis; Acemannan
Immunostimulant, an injectable as an adjunct for the treatment of fibrosarcoma in dogs and cats; raw materials, such as Manapol Powder used in a variety of consumer and nutraceutical products; and acemannan
hydrogel used in Carrington's proprietary wound care products.
vera possesses various biological and physiological activities in cosmetology and medicine: healing ability of skin burns and cutaneous injuries; prophylactic effect against radiation leucopenia; antiulcer; inhibitory action against some bacteria and fungi; inflammation-inhibiting effect; inhibition of the prostaglandin synthesis by anthraquinone-type compounds; and inhibition of the AIDS virus by acemannan
, the major carbohydrate fraction in the gel, is a water-soluble long chain mannose polymer which accelerates wound healing, modulates immune function (particularly macrophage activation and production of cytokines) and demonstrates antineoplastic and antiviral effects [28,29,30].