acanthocyte

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Related to Acanthocytes: abetalipoproteinemia, target cells

a·can·tho·cyte

(ă-kan'thō-sīt),
An erythrocyte characterized by multiple spiny cytoplasmic projections, as in acanthocytosis.
[acantho- + G. kytos, cell]

Acanthocyte

A densely stained spheroidal red cell with multiple (usually 5–12), irregularly distributed, thorn-like spicules of variable size, often with drumstick ends.
Aetiology Hereditary abetalipoproteinemia* (hereditary acanthocytosis), severe (end stage) liver disease, hepatorenal failure, anorexia nervosa, chronic starvation. A small number of acanthocytes may be seen in severe haemolytic anaemia, especially post splenectomy, haemolytic anaemia due to pyruvate kinase deficiency, in neonatal hepatitis, after heparin administration, and rarely also in otherwise normal blood smears (one or two per smear), where they correspond to older, effete red cells approaching their “expiration” date of 120 days.
*Accompanied by decreased total serum lipids, phospholipids, cholesterol, vitamin E, vitamin A

acanthocyte

Acanthrocyte Hematology An RBC with a irregularly spaced, pointed spicules, of varying shape and number–Greek, ακαντηο, spike; acanthocytes are seen in abetalipoproteinemia–hereditary acanthocytosis, as well as in alcoholic cirrhosis with hemolytic anemia, hemolytic anemia due to pyruvate kinase deficiency, in neonatal hepatitis, after heparin administration or splenectomy. See Red blood cells.

a·can·tho·cyte

(ă-kan'thō-sīt)
An erythrocyte characterized by spiny cytoplasmic projections.
[acantho- + G. kytos, cell]
References in periodicals archive ?
3E would have been retrospectively classified as an acanthocyte, which was not a class label that was found in the top-3 model suggestions.
(a) Data set Training Validation Test Normal 728 81 203 Echinocyte 226 25 63 Dacrocyte 64 7 18 Schistocyte 546 61 152 Elliptocyte 66 7 18 Acanthocyte 120 13 33 Target cell 523 58 145 Stomatocyte 79 9 22 Spherocyte 173 19 48 Overlap 166 18 46 (a) Cells were randomly distributed 80:20 between training and test sets, respectively.
The most important diagnosis criteria of neuroacanthocytosis is the detection of acanthocytes in the peripheral blood; however, a diagnosis based on acanthocytes alone, without considering the clinical picture, may lead to a medical error (6, 7).
Despite the different ratios reported by various sources, it is generally accepted that the ratio of acanthocytes in the peripheral blood in neuroacanthocytosis cases is 5% of total erythrocytes (2).
Silveira also present hymenial acanthocytes, however their basidiospores are much smaller (up to 8 x 5 [micro]m).
A new species of Stropharia with hymenial acanthocytes. Mycologia 99: 135-138.
Acanthocytes of Stropharia rugosoannulata function as a nematode-attacking device.
rugosoannulata have to produce organs of capture (three-dimensional networks of hyphal loops produced by anastomosis, adhesive knobs or non-constricting rings, large spike cells, acanthocytes) (Fig.
Acanthocytes typically comprise 50% to 100% of erythrocytes in ABL and may result from vitamin E deficiency or altered membrane lipid composition.
A variant of band 3, 5HT, promotes the formation of acanthocytes,[37] presumably through the binding of band 3 to the cytoskeleton.
Q Our lab currently examines blood smears and reports the term poikilocytosis in addition to the individual terms of spherocyte, acanthocyte, and the like.
We've eliminated "occ'l" when describing elliptocytes, target cells, burr cells, schistocytes, acanthocytes, and teardrop cells.