Acanthamoeba infection | definition of acanthamoeba infection by Medical dictionary
Acanthamebiasis An infection by Acanthamoeba spp, which is characterised by pustules, vasculitis, granulomatous amoebic encephalitis, and granulomas of skin. It is common in immunocompromised or immunosuppressed individuals, and may lead to death.
High-risk AIDS, alcohol abuse, diabetes, immunosuppression-transplantation-related, cancer—leukaemia, lymphoma—malnutrition
Management Chlorhexidine, propamidine, miconazole nitrate
acanthamoeba infection Infection, with various species of the genus Acanthamoeba . Acanthamoeba culbertsoni is a ubiquitous soil AMOEBA that may cause infection in people who have suffered facial injuries or who have DIABETES or LYMPHOMAS. Abscess-like masses occur in the skin, lungs, middle ear and even the brain. Infection of the CORNEA can also occur in contact lens wearers, usually from Acanthamoeba polyphaga . Acanthamoeba cysts are impervious to chlorine in concentrations up to 50 parts per million. They may therefore survive in domestic water supplies. Treatment is with AMPHOTERICIN-B.
References in periodicals archive
26] discussed the relation between Acanthamoeba infection
of the central nervous system causes chronic granulomatous amebic encephalitis (GAE), and is usually associated with patients having a pre-existing condition such as AIDS, or other chronic illnesses which contribute to an immunocompromised state.
Disseminated acanthamoeba infection
is a rare disease characterized by widespread granulomatous infiltration of the skin and extracerebral organs; it usually occurs in immunocompromised patients.
However, a negative culture does not necessarily rule out Acanthamoeba infection
To treat the Acanthamoeba infection
, the patient was started on oral itraconazole and intravenous metronidazole; IV pentamidine was added 2 days later.
They conclude that Acanthamoeba infection
rates appear to be closely related to improper maintenance and cleaning of soft lenses by users.
Evidence of Acanthamoeba infection
was recently found by PCR in brain tissue of a patient with lupus, even without isolating the ameba (8).
In conclusion, Acanthamoeba infection
was demonstrated by hematoxylin and eosin and immunostaining of brain tissue and PCR detection of ameba mitochondrial DNA in brain tissue.
The increasing importance of Acanthamoeba infections