Absolute Configuration

Also found in: Dictionary, Encyclopedia, Wikipedia.

Absolute Configuration

A term of art referring to the arrangement of atoms around a molecule’s chiral centre.

Mentioned in ?

References in periodicals archive ?

Circular dichroism, a powerfull tool for the assessment of absolute configuration of flavonoids.

ACE inhibition by astilbin isolated from Erythroxylum gonocladum (Mart.) O.E. Schulz

6 ASSIGNMENT OF THE ABSOLUTE CONFIGURATIONS OF NATURAL PRODUCTS BY MEANS OF SOLID-STATE ELECTRONIC CIRCULAR DICHROISM AND QUANTUM MECHANICAL CALCULATIONS

Research and Markets: Comprehensive Chiroptical Spectroscopy, 2 Volume Set

Their focus is on the principles that govern relative and absolute configurations in transition state assemblies.

Principles of asymmetric synthesis, 2d ed

The next five chapters discuss separations, offering treatments of resolution of chiral drugs and drug intermediates by crystallization, isolation and production of optically pure drugs by enantioselective (able to select one of a chiral pair) chromatography, stereoselective chromatographic methods for drug analysis, capillary electrophoresis coupled to mass spectrometry for chiral drugs analysis, and chiral molecular tools for preparation of enantiopure alcohols and simultaneous determination of their absolute configurations by x-ray crystallography or anisotrophy methods.

Chirality in drug research

The book begins with an overview of chirality, with a discussion of absolute configurations and system descriptors, physical properties of enantiomers, and principles of resolution and preparation of enantiomers.

Chirality in Transition Metal Chemistry: Molecules, Supramolecular Assemblies and Materials Exposed