Absolute Risk Reduction


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Absolute Risk Reduction

Epidemiology A measure of the treatment effect, comparing the probability—or mean of a type of outcome in the control group—with that of a treatment group.
EBM The absolute arithmetic difference in the risk—i.e., the rate of an adverse event or outcome—between a study (treated/experimental) population and a control population.
References in periodicals archive ?
The difference in absolute risk reduction between Michigan and its neighbors is not attributable to a greater rate of facility closure over time in Michigan.
Example of How to Calculate Absolute Risk, Absolute Risk Reduction, Relative Risk, and Relative Risk Reduction (a)
Those in the absolute risk reduction condition received "For people with symptoms of arterial disease, aspirin can reduce the risk of having a stroke or heart attack: 8% of such people who did not take aspirin had a stroke or heart attack, compared to 7% of such people who did take aspirin.
Absolute risk reduction (ARR) = risk of the outcome in the control group minus risk of the outcome in the treatment group.
Formula: Absolute risk reduction (ARR) divided by control response rate, as a percent.
The analysis of all patients showed that the absolute risk reduction of upper GI complications was 0.
The absolute risk reduction for occurrence of antibiotic associated diarrhea was 22% (95% confidence interval, 0.
While this may be expressed as a highly significant 50 percent relative risk reduction for mortality, the absolute risk reduction is only 5 percentage points.
This US FDA's approval is based on the results from the company's landmark LEADER trial, which demonstrated that Victoza significantly reduced the risk of a three component endpoint consisting of cardiovascular death, non-fatal heart attack or non-fatal stroke by 13% vs placebo with an absolute risk reduction (ARR) of 1.
Researchers concluded that in this trial, an energy-unrestricted Mediterranean diet supplemented with either extra-virgin olive oil or nuts resulted in an absolute risk reduction of approximately three major cardiovascular events per 1,000 person-years, for a relative risk reduction of approximately 30%, among high-risk persons who were initially free of cardiovascular disease.