abdominoperineal resection


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abdominoperineal resection (APR),

a surgical cancer treatment involving resection of the lower sigmoid colon, rectum, anus, and surrounding skin and formation of a sigmoid colostomy; performed as a synchronous or sequential transabdominal and perineal procedure.

abdominoperineal resection

The surgical excision of the lower rectum and anus, resulting in the loss of the anal sphincter and a need for colostomy.

Results
Local control, 60–80%; 60–90% 5-year survival; for larger lesions, RT and 5-FU and mitomycin are used. 

APR is less preferred than RT for small lesions + external beam treatment or with radioactive implants—e.g., 198Iridium seeds.

ab·dom·i·no·per·i·ne·al re·sec·tion

(ab-dom'i-nō-per-i-nē'ăl rē-sek'shŭn)
A surgical treatment for cancer involving resection of the lower sigmoid colon, rectum, anus, and surrounding skin, and formation of a sigmoid colostomy; performed as a synchronous or sequential transabdominal and perineal procedure.
References in periodicals archive ?
Successful treatment has been reported with methods, such as abdominoperineal resection (APR) and pelvic exenteration, using wide local excision.
Since being diagnosed she has had chemotherapy, lung surgery, abdominoperineal resection surgery and now has a permanent stoma bag and is on dialysis.
There were 7 (5.9%) patients with wound infections necessitating opening of the port stitches and drainage of superficial infection, bleeding was seen in 5(4.2%) requiring conversion to open, three patients (2.5%) developed intra abdominal abscess following anterior resection, abdominoperineal resection (APR) and transabdominal preperitoneal (TAPP) inguinal hernia requiring percutaneous drainage under ultrasound guidance.
Patients with adenocarcinoma of the rectum within 5 cm from the anal verge underwent abdominoperineal resection and those with tumor above 5 cms.
Extended abdominoperineal resection with gluteus maximus flap reconstruction of the pelvic floor for rectal cancer.
The exception to this is perhaps with sigmoidorectal intussusception in which initial reduction may avert an abdominoperineal resection and a permanent colostomy, but this remains contentious.
After about one month, the patient underwent abdominoperineal resection of the rectum, which relieved his anal pain, but subsequently he developed perineal pain and dysuria.
However, in cases in which a tumor-free distal resection margin is not achievable, a locally far-advanced tumor is present, and the patient shows severely decreased anal function preoperatively, surgeons should perform abdominoperineal resection (APR) requiring a permanent colostomy.
In the robotic-assisted surgery group, nine patients underwent anterior resection (42.9%), seven underwent low anterior resection (33.3%), four underwent ultra-low anterior resection (19%), and only one patient (4.8%) underwent abdominoperineal resection (APR).
Abdominoperineal resection (APR) is one of the techniques performed in the surgical treatment of the distal rectal cancer [1].
Additionally, this modality allows the surgeons to perform sphincter saving procedure instead of abdominoperineal resection and permanent ileostomy construction.