AZT


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zidovudine

 [zi-do´vu-dēn]
a nucleoside analogue to thymidine, used as an antiretroviral agent in treatment of patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS); administered orally or intravenously. It was the first agent approved for such use.

AZT

Abbreviation for azidothymidine. See: zidovudine.

AZT

zidovudine.

AZT

(ā′zē-tē′)
n.
An antiviral drug, C10H13N5O4, that is a nucleoside reverse transcriptase inhibitor and is used in combination with other drugs for the treatment of HIV infection. Also called zidovudine.

AZT

a trademark for a human immunodeficiency virus inhibitor (zidovudine). Also called Retrovir.

AZT

A nucleoside analogue used with other anti-HIV agents to manage AIDS and HIV infection.
 
Adverse effects
Long-term AZT use is associated with muscle loss, nausea, anaemia, myelosuppression, oral ulcers, bone marrow damage and headache.

AZT

3'-azido-3'-deoxythimidine, zidovudine, Retrovir AIDS A nucleoside analogue, used with other anti-HIV agents to manage AIDS and HIV infection Adverse effects Long-term AZT use is associated with muscle loss, nausea, anemia, myelosuppression, oral ulcers, BM damage, headache. See AIDS, HAART.

AZT

Abbreviation for azidothymidine.
See: zidovudine

AZT

Abbrev. for azidothymidine or Zidovudine. A drug used in attempts to control AIDS. The drug is toxic but does seem to be able to prolong life. A short course of AZT has been shown to be capable of halving the incidence of transmission of HIV from mother to baby. AZT is now commonly used in combination with other anti-HIV drugs especially protease inhibitors.

AZT

Abbreviation for azidothymidine.
See: zidovudine.

AZT,

n the abbreviation for azidothymidine. See also azidothymidine.

AZT

azidothymidine.
References in periodicals archive ?
His book, Debating AZT, alerted President Mbeki to the toxicity issues of AZT in late 1999.
Similarly, researchers at a Brazilian university published a study in the June issue of the Journal of Acquired Immune Deficiency Syndrome that concluded that HIV-positive infants exposed to AZT were five to six times as likely to develop full-blown AIDS as HIV-positive infants who were not exposed to AZT.
Approved June 19, 1992 for combination use with AZT for the treatment of selected patients with advanced HIV disease.
9] Thus in conditions of genuine uncertainty as to the comparative merits of the two AZT regimens, enrolled subjects have a right to, and researchers a correlative duty to provide, either the short course AZT or the 076 regimen, thereby making the use of a placebo arm in the international studies unethical.
A study by the National Institute of Child Health and Human Development in Washington combined the findings of that study with several others in Europe and North America and found that Caesarean sections reduced transmission by half and, when combined with AZT treatment, cut transmission to just two per cent.
Researchers have subsequently shown that this AZT regimen has reduced perinatal transmission in other populations in which AZT has been used.
A study based on persons with AIDS (PWAs) in Maryland indicates that women are less likely to receive AZT than linen (Moore et al.
chief of the HIV infections branch of the Hospital Infections Program for the CDC, gave an update on the use of AZT following needlestick exposure.
The National Institutes of Health is claiming the National Cancer Institute should have been named coinventor of the drug, which would enable the NIH to license other companies to produce AZT at a lower cost.
In critiquing the medical-industrial complex and the orthodox old-boy AIDS network, Good Intentions adds to the history of AIDS, bringing to life the people who shepherded the drug AZT from laboratory to patient.
However, AZT is the only drug approved for treating the AIDS virus (HIV) itself.