AURKCA gene on chromosome 19q13.43 that encodes Aurora kinase C, which is involved in regulating many mitotic events. Aurora C is the serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), which is critical for the correct progression through and completion of mitosis. It has redundant cellular functions with AURKB; both phosphorylate histone H3. AURKC also phosphorylates TACC1, another protein involved in cell division.
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