ATRA


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Related to ATRA: ATTRA, ATRA syndrome

ATRA

A vitamin-A analogue used to manage acute promelocytic leukaemia, with the translocation t(15;17) or typical PML-RAR gene rearrangement, as it prompts the leukaemic cells to maturation.

Adverse effects
Headaches, dry skin, mouth and eyes, nausea, bone pain.
References in periodicals archive ?
atra extract needed to kill 50% and 90% of the treated larvae 24 hours post -treatment for this extract were 188.
We have succeeded in rescue of a patient who developed intracranial hemorrhage before treatment using initial single administration of ATRA for 5 days followed by concomitant chemotherapy with ATRA after improvement of DIC.
These patients not only fail to respond to ATRA but also are resistant to ATO and anthracycline and therefore cannot be treated with the conventional APL regimen.
Under ATRA, the taxpayer is permitted to execute an in-plan Roth rollover much earlier in his or her career rather than waiting until age 59 1/2.
Apart from ATRA, the biggest impact for some taxpayers in 2013 and going forward and back, if affected taxpayers amend prior tax years that are still open--was from the U.
In light of ATRA, grantors should consider how to fund life insurance products, Cymbal said.
The ATRA is the only rating agency using an objective mathematical multi-criteria approach taking into account the complexity of airlines safety in order to generate robust, reproducible and meaningful results, without any arbitrary weighting systems, the agency said.
ATRA extended some of the shorter write-off periods and accelerated deductions for certain types of property.
Investigations revealed APL (see Table 1 for other investigations), and he was started with daily oral administration of ATRA 45 mg/[m.
In preclinical models, tamibarotene has proven to be 10 times more potent than ATRA with milder side effects.