ATR

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ATR

A gene on chromosome 3q22-q24 that encodes a protein belonging to the PI3/PI4-kinase family, which is closely related to ATM, the protein kinase encoded by the gene mutated in ataxia telangiectasia. ATR is similar to the cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage; it phosphorylates checkpoint kinase CHK1 and checkpoint proteins RAD17 and RAD9, as well as tumour suppressor protein BRCA1.

Molecular pathology
ATR mutations cause Seckel syndrome.

ATR

Achilles tendon reflex, see Ankle reflex.

References in periodicals archive ?

70 Kempton 12.50-3.45 Jumps 6 races PS367k CH4/RUK 32 Wetherby Inspection: 8.30am 12.35-3.30 Jumps 6 races PS70k CH4/RUK 40 Wincanton 12.30-3.55 Jumps 7 races PS51k RUK 48 Wolverhampton Jackpot 1.40-4.45 Flat 7 races PS39k ATR 54 Ffos Las 12.35-4.00 Jumps 7 races PS37k ATR 60 Sedgefield 12.10-3.35 Jumps 7 races PS30k ATR 78 Fontwell Inspection: 8am 12.20-3.50 Jumps 7 races PS23k ATR 82 Market Rasen 12.25-3.20 Jumps 6 races PS23k RUK 88 Towcester 12.45-3.40 Jumps 6 races PS20k ATR 94 Leopardstown 12.20-3.30 Jumps 7 races [euro]196k RTE2/ATR 104 Limerick 12.35-3.45 Jumps 7 races [euro]109k ATR 111 Down Royal 12.25-3.30 Jumps 7 races [euro]63k ATR 30 Santa Anita TRAINERS were allowed to declare horses for two races.

RACING POST TODAY

58 Cheltenham Tote Jackpot 1.15-4.05 Jumps 6 races PS147k CH4/RUK 36 Lingfield (A.W.) 12.00-3.55 Flat 8 races PS38k ATR 46 Newcastle 12.20-3.45 Jumps 7 races PS29k ATR 72 Wolverhampton (A.W.) 4.15-7.45 Flat 8 races PS31k ATR 82 Dundalk (A.W.) 6.00-9.25 Flat 8 races PS86k ATR 34 Jebel Ali 10.55 SIS ENTRIES & RESULTS Tomorrow (GB) ......................29 Sunday (declare today) ..............31 Tuesday ................................32 Wednesday............................33 Index to entries ....................28 Results ................................102 Birthdays ................................4 Chatroom ................................4 Pricewise ................................9 Eddie Fremantle ..................

RACING POST TODAY

56 Down Royal 1.05-4.10 Jumps 7 races [euro]155k ATR 82 Dundalk 6.00-9.25 Flat 8 races [euro]81k ATR 62 Newmarket 12.40-3.55 Flat 7 races PS74k RUK 32 Wetherby Tote Jackpot 1.00-3.45 Jumps 6 races PS59k RUK 48 Uttoxeter 12.50-4.05 Jumps 7 races PS25k ATr 74 Wolverhampton 4.15-7.45 Flat 8 races PS25k ATR 42 Santa Anita 8.06-11.30 Flat 6 races ATR 38 Jebel Ali 10.05-1.05 Flat 6 races SIS Horse Play ..............................4 Bill Barber ..............................