ATP1A1
(redirected from ATPase, Na+/K+ transporting, alpha 1 polypeptide)ATP1A1
A gene on chromosome 1p21 that encodes an alpha 1 (catalytic) subunit of the family of P-type cation transport ATPases and subfamily of Na+/K+ -ATPases. These Na+/K+ -ATPases are heterodimers composed of a large alpha subunit and a smaller beta subunit, and are responsible for establishing and maintaining the electrochemical gradients of Na and K ions across plasma membranes. These electrochemical gradients are required for osmoregulation, sodium-coupled transport of various organic and inorganic molecules and electrical excitability of nerve and muscle.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.