ATP5C1

A gene on chromosome 12q13.13 that encodes a subunit of mitochondrial ATP synthase, an enzyme that catalyses ATP synthesis, utilising an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: a soluble catalytic core and F1—which consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, a single subunit of the other 3, as well as a membrane-spanning component, Fo, which comprises the proton channel. ATP5C1 encodes the gamma unit of the catalytic core.

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ATP5C1P1

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Using DAVID, we found that hypermethylated genes in ESC cells are mostly enriched with the regulation of cell cycle (FZR1, E2F5, BOP1, TRRAP, CDK4, JUNB, etc.), cell death (SIVA1, MCL1, YPEL3, ARF6, UBQLN1, SHF, CIAPIN1, APLP1, GPX1, CASP3, etc.), and mRNA metabolic process (SCAF1, FIP1L1, STRAP, RBM15B, CWC15, XAB2, YBX1, AUH, SF3B2, APLP1, HNRNPL, etc.); the hypomethylated genes are enriched with functions related to ATP synthesis (ATP6V1F, ATP6V1C1, ATP6V0C, ATP6V1A, ATP6V0E, ATP6V1E1, ATP5C1, etc.) and mitochondrial ribosome (MRPL15, MRPL27, MRPL16, MRPL36, MRPL39, MRPL34, DAP3, etc.) (Excel Sheet S2).

Topological Characterization of Human and Mouse [m.sup.5]C Epitranscriptome Revealed by Bisulfite Sequencing

Through coexpression network construction and analysis of node degree, we found some functional and high connected hubs varied in EC and HIP region, such as CHRM1, MAPK1, TGFBR1, LIFR, ERBB4, ERBIN, ATP5C1, IGF1R, GJA1, TJP1, AP2M1, CDK5, FGF2, TUBB, SLC22A3, DBT, CDK13, NLN, and MIF.

The Bioinformatic Analysis of the Dysregulated Genes and MicroRNAs in Entorhinal Cortex, Hippocampus, and Blood for Alzheimer's Disease

These genes included succinate dehydrogenase (SDHC), cytochrome c oxidase (COX5B/ COX6B), and various genes of the ATP synthase complex (ATP5G1, ATP5C1, ATP5J, ATP5B, ATP5A1, ATP50, and ATP5F1).

Molecular mechanisms of West Nile virus pathogenesis in brain cells

subunit of Na+/K+-gTPase FACL6 Fatty acid Coenzyme A ligase long-chain 6 ATP1B1 Beta subunit of Na+/K+ATPase MGLL Monoglyceride lipase ATP5C1 ATP synthase H+ transporting mitochondria) F1 complex PDHA2 Pyruvate dehydrogenase E1 alpha 2 ASPH Aspartylbeia-hydroxylase 1_965027 Containing a cache domain PECI Peroxisomal D3, D2-enoyl-CoA isomerase TXNIP Vitamin D-3 up-regulated protein-1 Unknown FLJ22662 Unknown MGC13269 Unknown AGTPBPt Unknown TRAP25 Unknown 1_1100083 Unknown Ctorf21 Unknown KIAA0125 Unknown HSPC053 Unknown DKFZp434G0920 Unknown 1_1151996 Unknown Myocardium (Myoc) metastatic neuroblasts.

ppGaINAc-T 13: a new molecular marker of bone marrow involvement in neuroblastoma

Among the genes highly expressed in the resistant ALL cells were Brutori s tyrosine kinase and two ATP synthesases (ATP5A1 and ATP5C1).