Also found in: Dictionary, Thesaurus, Financial, Acronyms, Encyclopedia, Wikipedia.


A locus on chromosome 5p13.1-p12 that encodes glial-cell-derived neurotrophic factor, which enhances survival and morphological differentiation of dopaminergic neurons and increases high-affinity dopamine uptake. It is a ligand for the product of the RET (rearranged during transfection) proto-oncogene.

Molecular pathology
GDNF mutations may be associated with Hirschsprung disease.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Molecular virology Activating transcription factor A cellular protein that stimulates transcription of adenovirus E4 transcription unit, which acts early in infection at any of several 'enhancer' binding sites
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Some notes of interest were that, in addition to scheduled appointments, some exhibitors were surprised by a large number of walk-ins, and that it is advisable to capture the interest of Indonesian buyers fast because, as it was succinctly explained by one exhibitor, "for them ATF is a day-and-a-half market.
"Further, ATF has previously determine that non-standard AR-type upper assemblies, when attached to an AR-type receiver, does not preclude the upper assembly from being classified as a firearm "receiver.
Before joining ATF, Jones served as a police officer with the Charlotte-Mecklenburg (N.C.) Police Department for four years.
Mr Ansari said the ATF needed immediate reconstruction of its parade ground, installation of a tubewell, housing colony and a training school which would cost Rs84 million.
Inspector General of Police Moazzam Jah Ansari, addressing the ATF passing-out ceremony, said that Balochistan police had rendered matchless sacrifices against terrorism due to which law and order situation improved in the province.
ATF has already acquired the system's hardware, and the form-generating system is accessible on the represented manufacturers' websites.
Their selection was primarily due to their ATF resistance, their ability to maintain sealing performance over a broad temperature range, and specifically their ability to seal at very low temperatures.
Aziz Tabba Foundation (ATF) was established in 1987 as a not-for-profit trust.
On a tip-off, the ATF conducted combing operation in Dera Ghazi Khan and the terrorists were asked to lay down their arms before Law enforcing agencies.
"Look, we don't have the people." Ray, an ATF spokesman, reels off some facts: More than 10 million guns are made in the United States every year, and another 5 million are imported.
The tourism ministers of the 10 member-countries of the Association of Southeast Asian Nations (Asean) are meeting in Manila at the staging of the 35th Asean Tourism Forum (ATF) this month to map out an integrated tourism development plan and policy framework for the entire region.
The groundswell of public and congressional opposition against the ATF's proposed ban on 5.56 mm M855 rifle ammunition was so swift and strong that the agency announced on March 10 that it was backing down.