CORIN

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CORIN

A gene on chromosome 4p13-p12 that encodes a serine-type endopeptidase which converts non-functional propeptide NPPA into active atrial natriuretic peptide hormone, resulting in natriuresis, diuresis and vasodilation. CORIN may also process pro-NPPB, the B-type natriuretic peptide.

Molecular pathology
Defects in CORIN cause pre-eclampsia/eclampsia type 5.
References in periodicals archive ?
Agilent's ATC2 solution for Xilinx FPGAs is part of the ChipScope tools and can be configured in either a state or timing mode.
Alternatively, in the timing mode, the selected signals are not latched but instead propagate through the ATC2 core mux to external instrumentation.
The ATC2 tool includes built-in test-signal generation that simplifies specification of external logic analyzer connections.
As in the Textronix and Altera solution, the ATC2 core plus external instrument supports combined probing of both FPGA and board-level signals.
According to Joel Woodward, senior product manager, FPGA debug at Agilent, "The ATC2 core has been designed so that it could be added with minimal modifications to the design flow or the design itself.
Gaining access to low cost inputs might favorably shift the firm's average total cost curve (from ATCI to ATC2), as shown in Figure 4, whereas the demand curve (D) remains unaffected.