ASSENT 3 PLUS

Assessment of the Safety of a New Thrombolytic-3 Plus. A clinical trial comparing enoxaparin and unfractionated heparin in prehospital management of acute myocardial infarction; ASSENT 3 PLUS failed to meet its primary outcome.

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ASSENT 3 PLUS was jointly sponsored by TNKase global marketing partner Boehringer Ingelheim and Aventis Pharma AG.

Genentech (NYSE:DNA) has announced that results from the ASSENT 3 PLUS trial demonstrate pre-hospital administration of the single-bolus thrombolytic (clot-dissolving) agent TNKase(TM) (Tenecteplase) to patients suffering from acute myocardial infarction (AMI, or heart attack) to be technically feasible and faster than in-hospital treatment.

The 1,639-patient, international, multicenter, randomized, open-label ASSENT 3 PLUS clinical trial was a satellite study of the larger hospital-based ASSENT 3 trial.

Lars Wallentin, Uppsala University, Uppsala, Sweden, and principal investigator of the ASSENT 3 PLUS study.

PRE-HOSPITAL THROMBOLYTIC HEART ATTACK TREATMENT FEASIBLE

Genentech (NYSE:DNA) today announced that results from the ASSENT 3 PLUS trial demonstrate pre-hospital administration of the single-bolus thrombolytic (clot-dissolving) agent TNKase(TM) (Tenecteplase) to patients suffering from acute myocardial infarction (AMI, or heart attack) to be technically feasible and faster than in-hospital treatment.

Pre-hospital Thrombolytic Treatment of Heart Attack Found Feasible and Faster Than In-hospital Therapy

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