ASC-US


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Related to ASC-US: colposcopy, ASC-H

ASC-US

, ASCUS
atypical squamous cells of uncertain significance It is a finding on some abnormal PAP smears in which frankly dysplastic lesions are not found, but cell nuclei demonstrate minor histopathological abnormalities.
References in periodicals archive ?
This finding differs from large, conventional test series in which ASC-US test results have been the most-common, abnormal Pap result (36%-39%) preceding CIN 2/3 diagnoses.
In adolescents with ASC-US and HPV positive or with LSIL, it is now recommended to watch and wait, and repeat the Pap in one year.
With the addition of more-predictive liquid-based Pap tests, the use of 2001 Bethesda terminology, the development of the American Society for Colposcopy and Cervical Pathology guidelines including HPV triage of ASC-US, and recently, the ability to use imager-guided screening, we sought to investigate the current proportion of ASC-US Pap tests leading to a high-grade histologic diagnosis.
If cytology at this first year of follow-up of the original ASC-US or LGSIL is HGSIL or greater, colposcopy should be done.
In these studies, cytology was evaluated with either ASC-US and above or L-SIL and above being used as the basis for referral after which H-SIL was detected on biopsy.
Although there is significant variability in interinstitutional HPV-positive rates in ASC-US Pap tests, monitoring the HPV-positive rate in ASC-US Pap tests is a valuable broad measure of quality.
Test accuracy for detecting CIN2 or higher in patients with ASC-US.
doing Hybrid Capture for HPV DNA on ASC-US positive Pap tests only.
The performance of p16INK4a immuno-cytochemistry (p16 Cytology) and HPV testing was analyzed on a series of 810 retrospectively collected ASC-US and LSIL cases.
Atypical Pap test interpretations, such as ASC-US, ASC-H, and AGC (including endocervical or endometrial glandular abnormalities) are excluded.
Routine HPV DNA testing of residual thin layer preparation samples from women with ASC-US may well be more cost effective than the traditional management of the past.