The other subunits are ARPC1, ARPC3, ARPC4, and ARPC5
and two actin related proteins Arp2 and Arp3 [6-9].
(177) There is also a significant group of miRNAs whose targets are associated with cell protrusions and the cytoskeleton, including transgelin 2 (TAGLN2), targeted by miR-1, (178) moesin (MSN), and actin-related protein 2/3 complex, subunit 5 (ARPC5
), targeted by miR-133a, (179,180) and podoplanin (PDPN) targeted by miR-363.
Mature monocytes expressing CD16 showed higher levels of genes and corresponding proteins associated with phagocytic activity mediated through Fc[gamma] receptor: actin-related protein 2/3 complex (ARPC5
), CD16, hemopoietic cell kinase (HCK), thyrosine-protein kinase Lyn (LYN), hemeoxygenase 1 (HMOX), villin 2 (VIL2).