ARNT


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ARNT

A gene on chromosome 1q21 that encodes aryl hydrocarbon receptor, which is involved in inducing several enzymes that participate in xenobiotic metabolism—e.g., of dioxin and polycyclic aromatic hydrocarbons—resulting in translocation of the ligand-binding subunit to the nucleus.

Molecular pathology
A t(1;12)(q21;p13) translocation, which results in a TEL-ARNT fusion protein, is associated with acute myeloblastic leukemia.
References in periodicals archive ?
James Arnt Aune, "The Politics of Rhetorical Studies: A Piacular Rite," Quarterly Journal of Speech 92, 1 (2006): 69-76.
Dana Cloud, Stephen Macek, and James Arnt Aune, "The Limbo of Ethnical Simulacra," Philosophy and Rhetoric 29, 1 (2006): 72-84.
Mercieca and James Arnt Aune, "A Vernacular Republican Rhetoric: William Manning's Key of Libberty," Quarterly Journal of Speech 91,2 (May 2005): 119-143.
James Arnt Aune, "Justice and Argument in Judaism: A D'Var Torah on Shofetim," Rhetoric & Public Affairs 7, 4 (Winter 2004): 449-460.
The calibrated RT-PCR showed good intraassay imprecision; the CV (calculated from 10 replicates of a sample) was 7.3%, 6.8%, 8.7%, 6.0%, and 6.9% for AHR, ARNT, CYP1B1, IL-1[beta], and [beta]-ACT, respectively.
The expression of AHR and related genes, expressed as amol mRNA/100 ng of total RNA, was 0.012-0.55 for AHR, 0.07-0.36 for ARNT, 0.02-6.14 for CYP1B1, 0.0150.33 for IL-1[beta], and 378-1940 for [beta]-ACT.
Weighted Deming regression analysis was performed on all data, and the regression coefficient (R), slope (95% confidence interval), and y-intercept (95% confidence interval) for each gene was as follows: for AHR, R = 0.951, slope = 0.90 (0.7-1.05), y-intercept = 0.05 amol (-1.22 to 1.32 amol); for ARNT, R = 0.912, slope = 1.0 (0.7-1.3), y-intercept = -2.09 amol (-6.1 to 1.9 amol); for CYP1B1, R = 0.948, slope = 1.14 (0.9-1.4), y-intercept = -0.22 amol (-2.19 to 1.73 amol); for IL-1[beta], R = 0.967, slope = 1.05 (0.9-1.2), y-intercept = 0.1 amol (-0.53 to 0.73 amol); for [beta]-ACT, R = 0.961, slope = 1.1 (0.9-1.3), y-intercept = -0.37 amol (-1.0 to 0.28 amol).
Responsiveness of the adult male rat reproductive tract to 2,3,7,8-tetrachlorodibenzo-pdioxin exposure: Ah receptor and ARNT expression, CYPIA1 induction, and Ah receptor down-regulation.
Coventry: 2.09 ARNT, Lee; 5.59 O'MARRA, Tendler, Goertzen (PP); 12.55 ARNT, DaCosta; 17.27 RAWLYK (PP); 43.34 LEE, DaCosta, Goertzen (PP) Belfast: 1.01 K PHILLIPS, Sawada, Sandrock Shots: Coventry 39, Belfast 34 Penalty minutes: Coventry 12, Belfast 20
Man of the match Ben Arnt celebrates his first goal of the night.