ARID3A

ARID3A

A gene on chromosome 19p13.3 that encodes a widely expressed ARID (AT-rich interactive domain) family transcription factor thought to be involved in B-cell differentiation and in controlling cell cycle progression by the RB1/E2F1 pathway. It is induced by p53/TP53 following DNA damage and interacts with BTK, E2F1 and GTF2I.
Mentioned in ?
References in periodicals archive ?
revealed that HMGA1, HMGA2, IGF2BP2, HIF3A, ARID3A, and E2F5 were the most highly induced targets of let-7 microRNAs in the context of intestinal homeostasis [31].
Let-7 also inhibits cell proliferation by regulating transcriptional factors such as STAT3, E2F5, E2F6, CBFB, PLAGL2, SOX9, GZF1, YAP1, GTF2I, and ARID3A [42, 43].