AREDS


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AREDS

Age-Related Eye Disease Study. A trial sponsored by the US National Eye Institute of the National Institutes of Health, which compared the effects of zinc and/or antioxidants to a placebo.
Conclusion Patients taking antioxidants and zinc had a significant reduction in the risk of advanced age-related macular degeneration.
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The AREDS study, as mentioned previously, was the crowning achievement for the nutrition community, and is THE work that is referenced today when discussing nutrition and eye health.
Macular Health's original supplement formulation was modeled after the results of AREDS I, released in 2001.
Consumers taking Lipotriad Visionary no longer need to worry about the potential danger of these dyes and can feel reassured that they are taking an AREDS 2 formula eye vitamin for macular degeneration that uses all natural coloring and is proven to help prevent and slow the progression of AMD.
We are thrilled that the NEI's AREDS II Study confirmed that the Macular Health eye supplement is truly the best formulation for those afflicted with Age-Related Macular Degeneration," said McAnnally.
Emily Chew, Deputy Clinical Director at the NEI and Deputy Director of the NEI Division of Epidemiology and Clinical Applications stated, "The addition of lutein and zeaxanthin to the AREDS vitamin formulation demonstrated a 10% decrease in the progression to advanced AMD.
Because all participants were at risk for worsening of their AMD, they were also offered the original or a modified version of the AREDS formulation (without omega-3 or lutein/zeaxanthin).
Bausch + Lomb, which supplied supplements for both AREDS trials, still sells the AREDS1 formula with beta-carotene (left) or with lutein in its place (not shown).
The AREDS study administered zinc in the form of zinc oxide, which is not well absorbed.
All participants were also asked to take the original AREDS formulation or accept a secondary randomization to 4 variations of the AREDS formulation, including elimination of beta-carotene, lowering of zinc dose, or both.
Based on apparent risks of beta carotene and possible benefits that are only evident within exploratory subgroup analyses, lutein + zeaxanthin requires further investigation for potential inclusion in the AREDS supplements.
EYEBAR (R) is a chocolate based nutraceutical which overcomes the palatability problems associated with traditional AREDS nutritional products for AMD.