AREDS


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AREDS

Age-Related Eye Disease Study. A trial sponsored by the US National Eye Institute of the National Institutes of Health, which compared the effects of zinc and/or antioxidants to a placebo.
Conclusion Patients taking antioxidants and zinc had a significant reduction in the risk of advanced age-related macular degeneration.
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AREDS found that in 3,640 people with intermediate signs of AMD, high doses of zinc oxide, copper (to balance out zinc supplementation), and the antioxidants vitamin C, vitamin E and beta-carotene (vitamin A) significantly reduced the risk for developing advanced AMD.
The aid is designed to guide practitioners to give the most up to date nutrition advice based on the AREDS 2 study.
AREDS2 is testing the same levels of vitamins C and E that were used in the original AREDS, but it's comparing lower vs.
Bausch & Lomb made the AREDS formulation available to consumers as Ocuvite PreserVision dietary supplements after the results of the ARED study were released in October 2001.
Two phytonutrients--lutein and zeaxanthin--were not included in AREDS and other studies, because researchers have only recently realized how important they are to eye health.
If they all took the AREDS supplements, it would prevent more than 300,000 cases of advanced macular degeneration during the next five years," says Ferris.
It is now suggested that 10mg of L and 2mg of Z are a safe and effective tool for the treatment of AMD as a combination with the original AREDS supplement, without beta-carotene.
In AREDS, we found supplements made a huge difference in eye health," says Fredrick Ferris, M.
The AREDS surprised me," says Julie Mares-Perlman of the University of Wisconsin.
The company developed HydroEye(R), a patented, oral formulation for dry eyes; OcularProtect(R), a comprehensive formulation to support eyes and overall body health; MacularProtect(R) Plus and MacularProtect(R) Complete, powerful formulations based on the AREDS clinical trial to preserve macular health; and other high-quality products for eye and body health.
The interpretation by The Pigment Research Group (OT July 12, 2013, page 36-37) seemed optimistic when compared to the AREDS group's own conclusions: "In summary, addition of lutein+zeaxanthin, DHA+EPA, or lutein+zeaxanthin and DHA+EPA to the AREDS formulation in primary analyses did not further reduce risk of progression to advanced AMD"--advanced AMD being defined as central geographic atrophy or CNV.
dagger]- Exact formula used in AREDS when taken at a dose of 4 tablets per day; label amounts are different because they reflect minimum contents throughout shelf life of product.