APUD cell


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APUD cell

(ā′pəd)
n.
A cell capable of amine precursor uptake and decarboxylation and of synthesizing and secreting polypeptide hormones.
References in periodicals archive ?
Neuroendocrine carcinoma (NEC) of the head and neck are thought to be derived from the APUD cell family (amine precursor uptake and decarboxylase system), more specifically the Kulchitsky's cells.
The APUD cell concept and its implications in pathology.
Those DNES cells secreting serotonin or certain other amine derivatives demonstrate amine precursor uptake and decarboxylation and are often referred to acronymically as APUD cells, e.
Review article--involvement of gastric APUD cells in chronic renal failure.
The epithelial cell layers of the anterior intestine were consisted mainly of columnar enterocytes, sac-shaped goblet and a few APUD cells (Figs.
Enteroendocrine cells are alternatively known as neuroendocrine cells and APUD cells because they were thought to originate from the neural crest.
Cytochemical identification of human and murine pituitary corticotrophs and somatotrophs as APUD cells.
19-22) Other theory is that SCC of the prostate arises de novo from APUD cells in the prostate (22), (23) and third theory is that SCC of the prostate arises from stem cells in the prostate.
28) Carcinoid tumors are known to derive from the neural crest or neuroendocrine (APUD) tissues, although we are not certain whether APUD cells are present in normal salivary glands.
Tumors arising from APUD cells may contain high amounts of NSE detectable by both immunostaining of tumor cells and radioimmunological measurement of extractable enzyme [2, 3].