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A gene on chromosome 21q21.3 that encodes a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form various peptides.

Molecular pathology
APP mutations are implicated in autosomal dominant Alzheimer’s disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).


Academy of Pharmaceutical Physicians and Investigators.
References in periodicals archive ?
Tufail said that APPI is an investment oriented agreement to harmonize investment related laws in all 10 countries.
After repeated complaints by traders and term clients, the APPI panel on April 1, 1997, introduced twice-weekly assessments to make them more responsive to changes in the spot market.
Because of a slow response by the APPI panel, spot market premia over this index have been eliminated.
For the last six years, APPI has used a local area network (LAN) and The Cat's Pajamas software to handle book fulfillment.
APPI uses the contracted warehouse and shipping service of Professional Mail Distribution Services (PMDS), Jessup, Maryland.