APOE genotype


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APOE genotype

A genetic variant with some use in the diagnosis of Alzheimer's disease and other dementias.
See also: genotype
References in periodicals archive ?
APOE Genotypes. The major APOE allelic variants [epsilon]2, [epsilon]3, and [epsilon]4 can be obtained from allelic combinations of the rs429358 and rs7412 polymorphisms.
It is widely acknowledged that APOE allele carriers are more likely to develop AD; however, the influences that APOE genotypes exert on PD are not exactly the same.
Age at onset of temporal lobe seizure and ApoE genotype polymorphism.
They showed that there were no differences in the ApoE genotype distribution between the diabetic group and the healthy group.
The first study evaluated frequencies of APOE genotypes and alleles in a population of Cayapas from Esmeraldas (n = 96) [19].
In order to evaluate the effect of the ApoE genotype on the birth weight in different SGA subtypes the proportional odds model was used to assess ordinal data.
A prospective study of the association between APOE genotype and the risk of myocardial infarction among apparently healthy men.
[18.] Aboud O, Mrak RE, Boop FA, Griffin WS (2013) Epilepsy: neuroinflammation, neurodegeneration, and APOE genotype. Acta Neuropathol Commun 1: 41.
The confirmed positive association of serum apoA-I with diabetes in Turkish women was independent of apoE genotype (e2/e3/e4) or of apoB levels (4), and serum apoE concentrations, independent of the apoE genotype, were strongly associated with hypertiglyceridemic dyslipidemias, especially with that accompanying elevated apoB (22, 23).
Results: The APOE genotype distribution in the patient group was as follows: [epsilon]3/[epsilon]3, 82.0%; [epsilon]3/[epsilon]4, 12.0%; and [epsilon]2/[epsilon]3, 6.0%.
This association in women remained robust in further analyses that adjusted for a history of stroke, age, education, and APOE genotype status.