acute panmyelosis with myelofibrosis
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acute panmyelosis with myelofibrosis
An aggressive form of acute myeloid leukaemia, in which the bone marrow is seriously damaged due to either a clonal expansion or toxic exposure, resulting in pancytopenia and poor prognosis (median survival post-diagnosis: 9 months).acute panmyelosis with myelofibrosis
,APMF
A form of acute leukemia in which multiple cell lines develop aberrantly, infiltrate internal organs, e.g., the spleen, and cause extensive bone marrow fibrosis.