APECED


Also found in: Acronyms.

APECED

[autoimmune polye ndocrinopathies, candidiasis, ectodermal dystrophies]

APECED

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. A subtype of mucocutaneous candidiasis characterised by increased immunoglobulins and decreased IgA, with progressive decline in parathyroid and adrenal function.
References in periodicals archive ?
Activity of amphotericin B, anidulafungin, caspofungin, micafungin, posaconazole, and voriconazole against Candida albicans with decreased susceptibility to fluconazole from APECED patients on long-term azole treatment of chronic mucocutaneous candidiasis.
Sillanpaa et al., "Critical immunological pathways are downregulated in APECED patient dendritic cells," Journal of Molecular Medicine, vol.
La hepatitis tambien se ha descrito en 10% al 20% de los pacientes con APECED. Alrededor del 20% de los casos desarrollan una HAI que se asemeja a una HAI tipo II (1).
Patients with CMC have a high incidence of endocrinopathies usually associated with APECED (see above).
Clinically, APECED comprises of a variety of autoimmune manifestations affecting mainly endocrine organs, such as parathyroid gland, thyroid gland, adrenal cortex and the gonads.
Because of delayed onset of diabetes and without a genetic analysis of AIRE gene, AIRE-related APECED in this patient remains hypothetic.
Defects in Aire expression result in autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) in human and multiorgan autoimmunity and serum autoantibodies in mice [57,62-64].
Podkrajsek et al., "Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines," Journal of Experimental Medicine, vol.
Mathis, "AIRE and APECED: molecular insights into an autoimmune disease," Immunological Reviews, vol.
http://www.aabainc.org 2,3,4,5 National Association of Anorexia Nervosa and Related Disorders PO Box 7 Highland Park, IL 60035 (847) 831-3438 (847) 433-4632 (fax) ??info@anad.org http://www.anad.org 2,3,4,5,6,7 APECED SYNDROME See: Ectodermal Dysplasia; Hypoparathyroidism APERT SYNDROME See also: Craniofacial Disorders Apert Syndrome Pen Pal Network PO Box 115 Providence, RI 02901 (401) 454-4849 2,3, APHASIA, ACQUIRED See also: Brain Injury/Stroke National Aphasia Association 156 Fifth Ave., Ste.
Westport, CT 06880 (203) 221-7350 (203) 221-9212 (fax) ??pullthrunw@aol.com http://www.pullthrough.org 1,2,3,4,9 APECED SYNDROME See: Ectodermal Dysplasia; Hypoparathyroidism APERT SYNDROME See also: Craniofacial Disorders Apert Support and Information Network PO Box 1184 Fair Oaks, CA 5628 (916) 961-1092 (voice/fax) ??apertnet@ix.netcom.com 1,2,3 Apert Syndrome Pen Pal Network PO Box 115 Providence, RI 02901 (401) 421-9076 3,5,9 Apert Syndrome Support Group 8708 Kathy St St.