AP2M1

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AP2M1

A gene on chromosome 3q28 that encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. AP2M1 is required for the activity of a vacuolar ATPase, which is responsible for proton pumping needed to acidify endosomes and lysosomes. It may also play a role in regulating the intracellular trafficking and function of CTLA-4 protein.
References in periodicals archive ?
Therefore, in this work, electric discharge machining of Aluminum (AP50) reinforced with various weight percentage of TiC particles prepared through powder metallurgy route have been studied and analyzed.
The alternative and classical complement pathways were suppressed confirming drug action (CH50 and AP50 hemolytic assays < 10%).
There were others, like the Suzuki AP50, the Malaguti, or even the bizarre Fantic Chopper.
Interaction of CTLA-4 with the clathrin-associated protein AP50 results in ligand-independent endocytosis that limits cell surface expression.
Despite efficient complement inhibition (AP50: 1%) and a normalised platelet count (180,000/[mm.sup.3]), the hemolysis persisted (haptoglobin < 20mg/dL) and kidney function continued to decline reaching a peak serum creatinine level of 7.2 mg/dL.
BIKES GOING UNDER THE HAMMER JAMES MAY 1974 Yamaha 49cc FS1-E - PS2,000-2,400 1976 Suzuki AP50 E - PS2,000-2,400 1980 Ossa 250cc MAR Trials Motorcycle - PS1,200-1,500 1979 Suzuki TS250 - PS800-1,200 1973 Honda CD175 - PS1,400-1,800 1975 Honda CB200 - PS1,500-1,800 1971 Kawasaki 250cc A1 Samurai - PS5,000-6,000 2010 Yamaha SR400 'Grievous Angel' by Deus Ex Machina - PS8,000-12,000 RICHARD HAMMOND Lot 334: 1977 Honda GL1000 Gold Wing - PS4,000-6,000 Lot 335: 2010 Norton Commando 961SE - PS14,500-18,500 Lot 336: 1970 Triton 500cc 'Cafe Racer' - PS6,500-8,500 Lot 337: 1975 Yamaha 49cc FS1-E - PS2,500-3,500
If you grew up in the 70s and early 80s you went from lusting after a Raleigh Chopper to wanting a Yamaha FS1-E or a Suzuki AP50.
Then, the right carotid artery was exteriorized and the AP50 catheter connecting to a pressure transducer (MP150, Biopac system, USA) was inserted into the left atria and left ventricle (LV) for the measurement of hemodynamic parameters LV systolic pressure (LVSP), LV end-diastolic pressure (LVEDP), maximal rate of LV systolic pressure (LV+dp/dtmax) and minimum rate of LV systolic pressure (LV-dp/dtmax).
Bigger bucks will get you autopilots such as Simrad's AP50 ($4,300 and up, depending on the exact model), which can handle pleasureboats of virtually any size and even take control of your bow thruster.
Rio Tinto Plc (LSE: RIO) (ASX: RIO) (NYSE:RTP), a UK-based mineral resources company, has announced that a company subsidiary, Rio Tinto Alcan, has been granted a loan from the Government of Quebec, Canada, for construction of the AP50 pilot plant in the Saguenay-Lac-Saint-Jean region of Quebec, Canada.
The government of Quebec has granted Rio Tinto Alcan $175 million to further the construction of its AP50 pilot plant in the Saguenay-Lac-Saint-Jean region.