ANXA9

ANXA9

A gene on chromosome 1q21 that encodes annexin 9, a low-affinity, calcium-dependent phospholipid-binding receptor for acetylcholine.

Molecular pathology
ANXA9 is targeted by keratinocyte autoantibodies in patients with pemphigus vulgaris.
References in periodicals archive ?
The Anxa9 gene was found to have significance between groups: P = .031, [[eta].sup.2] = .187.
A downregulation of the Anxa9 gene was found in the PTSD-vehicle group compared to the PTSD-midazolam group.
Gene # Group comparison Fold change Effect size P value Egr1 P-M versus P-V 1.01 0.218 * .011 Maoa C-M + L versus P-V 0.2 0.194 * .024 Anxa9 P-M versus P-V 0.67 0.187 * .031 S100a10 P-M versus P-V 0.38 0.166 .06 Gabrb2 P-M versus P-V 0.57 0.142 .123 Chrm2 C-M + L versus P-V 0.6 0.138 .138 Gene Description of gene Egr1 Long-term memory formation [50] Maoa Degrades biogenic amines, including catecholamines and serotonin [51] Anxa9 An atypical member of the annexin family of [Ca.sup.2+] and phospholipid-binding proteins, responsible for [Ca.sup.2+] coordination [52] S100a10 Intracellular p11 (S100a10) regulates serotonin receptor activity in psychiatric mood disorders [53].