PRPF6

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PRPF6

A gene on chromosome 20q13.33 that encodes protein involved in pre-mRNA splicing, which may be required in the tri-snRNP complex as a bridging factor between U5 and U4/U6 snRNPs in the late step of spliceosome assembly. It enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1.

Molecular pathology
Defects in PRPF6 cause retinitis pigmentosa type 60.
References in periodicals archive ?
Figure 3(c) presents the measured radiation patterns of E-phi for the MIMO antenna (Ant1) bent at 0[degrees], 30[degrees], 45[degrees], and 70[degrees].
qRT-PCR after let-7c-5p overexpression showed an inverse relationship with SLC25A4/ ANT1 , which was downregulated.
In 2012, ANT1 launched the first web TV in Cyprus with live broadcast and dedicated apps for smartphones.
To test their hypothesis, the researchers incapacitated the ANT1 gene in mice.
An Ant1 survey gave Disy 23 per cent, up from 16, and Akel 19, five points up since April.
"A company that is constantly posting losses, and especially losses of around 30 million (euros) a year over a three-year period cannot survive, while finding an investor becomes even harder," Michaelides told Ant1 TV.
Ant1 is abasic PIFA with the same dimensions of the proposed antenna 51 x 14 x 4 [mm.sup.3] (Figure 2(a)).
For example, ANT1 interacts with mtDNA [67], and its mutation causes a genetic disorder leading to multiple mtDNA deletions and autosomal dominant progressive external opthalmoplegia [116].
His appeal on the Greek television network ANT1 was made at a time of
TV STATION SHARES October 2012-March 2013 MAKED TV 0.6 ET-1 2.6 NET 6.9 ET-3 3.7 MEGA 20.3 ANT1 16.9 ALPHA 13.7 STAR 10.2 SKAI 8.6 Note: Table made from pie chart.
When quizzed by Greek journalists over the story which had appeared in two of the country's newspapers and on top TV stations ANT1 and MegaChannel yesterday, the Euro 2004 winner said: 'I do not know anything about this 'What I DO know is that I remain at Rangers.'