ANO1

ANO1

A gene on chromosome 11q13.2 that encodes anoctamin 1, a protein which is thought to act as a calcium-activated chloride channel; it is highly expressed in liver and skeletal muscle and is required for normal tracheal development.
References in periodicals archive ?
(106) C-kit (CD117) expression has also been recently reported in both low- and high-grade endometrial stromal sarcomas mimicking gastrointestinal stromal tumor; however, anoctamin 1 (ANO1, DOG1) immunostain, another diagnostic marker of gastrointestinal stromal tumor, has shown negativity and no mutations were identified in the KIT gene.
have recently demonstrated that chloride efflux through a [Ca.sup.2+]-activated [Cl.sup.-] channel, anoctamine 1 (Ano1), also called "transmembrane member 16A" (TMEM16A), is involved in mediating the glucose-stimulated insulin secretion [11].
Recently, Ano1, which was first found in gastrointestinal stromal tumour (GIST) and functions as a calcium-activated chloride channel, has been identified as a novel ICC marker in gastrointestine [6].
En Morelos, el sorgo es uno de los principales cultivos de temporal, con una produccion de 211,240.9 t ha-1 ano1 (SAGARPA, 2009).
Nas areas canavieiras do Brasil o total de precipitacao anual varia de 1.100 a 1.500 mm ano1 (Alfonsi et al., 1987).