nemaline myopathy type 5

(redirected from ANM)
Also found in: Acronyms, Wikipedia.

nemaline myopathy type 5

A form of nemaline myopathy (OMIM:605355), a family of muscular disorders characterised by muscle weakness of varying severity and onset, and abnormal thread- or rod-like structures in muscle fibres on histologic examination. NEM5 is a severe and progressive form seen in Old Order Amish. Affected infants display tremors with hypotonia and mild contractures of the shoulders and hips; proximal contractures progressively weaken and a pectus carinatum develops before infants die of respiratory insufficiency, often by age 2. 

Molecular pathology
Caused by defects of TNNT1, which encodes type-1 troponin T, the slow skeletal troponin T subunit.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
mit Anm. 23) geht hingegen mit der in der Historia Arabum des Rodrigo Jimenez de Rada uberlieferten Version auf eine eigenstandige Tradition zuruck; vgl.
A total of 69 AWW and 53 ANM during their scheduled monthly meetings were targeted in the study.
She facilitates preparation and implementation of the Village Health Plan along with Anganwadi worker, ANM, functionaries of other Departments and Self Help Group members.
Brad Newman, mentioned that Texas AnM was cloning, but it was when Dr.