ANA-negative systemic lupus erythematosus

ANA-negative systemic lupus erythematosus

Systemic lupus erythematosus (SLE) characterised by absence of antinuclear antibodies (which occurs in 5% of SLE patients), as well as photosensitivity, features of Sjögren syndrome, a low incidence of lupus nephritis and lupus psychosis, presence of rheumatoid factor and antibodies to Ro/SSA antigen and La/SSB antigens, and single-stranded DNA.
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