SOD1

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SOD1

A gene on chromosome 21q22.11 that encodes a soluble, copper- and zinc-binding cytoplasmic protein, which is responsible for destroying free superoxide radicals in the body, converting natural—but harmful—superoxide radicals to molecular oxygen and hydrogen peroxide.

Molecular pathology
SOD1 mutations have been linked to familial amyotrophic lateral sclerosis.
References in periodicals archive ?
The primers and PCR conditions used were previously described: ALS1 and ALS3 [17], HWP1 [18], SAP1 [19], SAP4-SAP6 [20], LIP1-LIP10 and PLB1-PLB2 [13], and CDR1 and MDR1 [21] (Table 1).
All of the isolated strains (n = 39) were carriers of the ALS1, SAP4-SAP6, LIP1, LIP2, LIP4, LIP6, LIP7, LIP9, LIP10, and PLB1-PLB2 genes.
In nearly all of the isolates, ALS1, HWP1, SAP4-SAP6, LIP1-LIP10, PLB1, and PLB2 were expressed after infection of the cell line A431, whereas CDR1 was expressed in 20 (51.
We found that each strain isolated that carried ALS1 (39/39) and ALS3 (14/14) was able to express these genes in the in vitro model of infection (Table 4).
The Candida albicans proteins and carbohydrates (and associated ALS1 antibody) were developed by James Cutler, Ph.
The ALS1 protein, a cell wall protein associated with Candida albicans, is an ideal target for a vaccine because it represents one of the structures that the fungus uses to attach to the host in the initial stages of infection.
Next in Nienstedt's cold cut line is the ALS1 automatic log saw, which reduces trimmed blocks to 16 long (482 mm) or short (254 mm) units per minute.