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ALLIANCEAggressive Lipid Lowering Initiation Abates New Cardiovascular Events. A clinical trial that assessed the outcomes of lipid-lowering therapy with atorvastatin (Lipitor) in patients with a history of coronary heart disease.
Primary endpoint Major acute cardiac events (MACE)—death, heart attacks, stroke, unstable angina requiring hospitalisation.
Conclusions Patients receiving Lipitor averaged 17% reduction in MACE, vs usual care; ±72% of Lipitor patients reached target LDL-C level vs 40% in patients receiving usual care.